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Many of the biological materials that researchers are most interested in studying, including those associated with major diseases, don’t lend themselves to the conventional methods that researchers ty...
Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;1...
The fruit fly may help us be less clueless about human muscle development and Parkinson's disease.Erika Geisbrecht, Kansas State University associate professor of biochemistry and molecular biophysics...
Wild type green fluorescent protein (wt-GFP) and the variant S65T/H148D each exhibit two absorption bands, A and B, which are associated with the protonated and deprotonated chromophores, respectively...
A thymidine phosphoramidite labelled at C6 with 13C has been synthesized, and incorporated into a synthetic oligonucleotide, d(CGCGT*T*GT*T*CGCG), which adopts a hairpin conformation. NMR relaxation m...
Chemically induced dynamic nuclear polarization (CIDNP) has been observed from yeast tRNAPhe following reaction with photoexcited riboflavin. At 20 OC, several resonances of tRNA in the native form sh...
The nuclear magnetic resonance (NMR) technique of chemically induced dynamic nuclear polarization (CIDNP) has been used to study the reactions between photoexcited flavins and a wide variety of nucleo...
This thesis describes separations performed by Pressurized Planar Electrochromatography (PPEC), which is a chromatographic method developed at IUPUI. In PPEC the mobile phase is driven by electroosmot...
To maximize the probability of obtaining an antibody peptidase, an efficient assay for the hydrolysis of peptide bonds was developed. Two methods for detecting the uncatalyzed rate of hydrolysis of a ...
Interaction of ribosomal protein L1 and the 23S rRNA plays an important role in both the structure and biological activity of the Escherichia coli ribosome. We have minimized the binding site for prot...
The Testis Specific Serine Kinase (Tssk) family of proteins is a large group of kinases that present high level of conservation within paralogs, as well as within species. In addition, in all reported...
Transport of proteins across membranes is essential during many stages of pathogen infection and colonization of human cells. Many Gram-negative pathogens use a Type 3 Secretion (T3S) system to inject...
Lysosomal storage diseases are disorders caused by deficiencies of enzymes responsible for the degradation of substances present in lysosomes. The loss of activity of a lysosomal enzyme leads to the a...
Because of the high cost of commercial genotyping chip technologies, many investigations have used a two-stage design for genome-wide association studies, using part of the sample for an initial disco...
Yale School of Medicine immunobiologist Ruslan Medzhitov, Ph.D., David W. Wallace Professor of Immunobiology and Howard Hughes Medical Institute Investigator, has been awarded the 2010 Lewis S. Rosens...

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