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A serendipitous finding lends new insight into how atopic dermatitis develops（图）
特应性皮炎 皮肤病 皮肤
2023/7/12
Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a ne...
Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
STAT6VT transgenic Atopic Dermatitis
2015/5/25
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the dis...
Food Habits in Atopic Patients in Iranian Children
Food Habits Atopic Patients Iranian Children
2015/9/25
The prevalence of allergic diseases has been increased during recent years; especially in industrialized countries.1 The relationship between allergic disease and genetic origins was proved while some...
Case Report of Restoration of the Corneal Epithelium in a Patient with Atopic Keratoconjunctivitis Resulting in Amelioration of Ocular Allergic Inflammation
allergic inflammation atopic keratoconjunctivitis conjunctiva corneal ulcer epithelium
2010/11/12
Background: Atopic and vernal keratoconjunctivitis are severe types of ocular allergic disease characterized not only by conjunctival inflammation but also by corneal involvement. In vitro studies hav...
Antitussive Effects of the Leukotriene Receptor Antagonist Montelukast in Patients with Cough Variant Asthma and Atopic Cough
atopic cough cough score cough variant asthma leukotriene receptor antagonist montelukast
2010/11/12
In patients with CVA, 2-week treatment with montelukast, clenbuterol, and montelukast plus clenbuterol all significantly decreased cough scores and treatment with montelukast plus clenbuterol was supe...
Teratogenic Effects and The Role in The Etiology of Atopic Diseases of Erythrosine (FD&C Red No.3)
Erythrosine (FD&C Red No.3) Food additives Food colours Atopy Teratogenicity
2009/7/2
Erythrosine (FD&C Red No.3, di sodium salt of 2,4,5,7-tetra-iodofluorescein); is used extensively as a colour additive in foods, drugs and cosmetics. Previous studies have shown that some of the food ...
Elevated Platelet Activation in Patients with Atopic Dermatitis and Psoriasis: Increased Plasma Levels of β-Thromboglobulin and Platelet Factor 4
atopic dermatitis platelet factor 4 platelets psoriasis β-thromboglobulin
2010/11/17
Our results show that blood platelets are activated in patients with AD or psoriasis, suggesting that activated platelets play a role in the pathomechanism of chronic skin inflammation. Furthermore, p...
Genetic Susceptibility to Atopic Dermatitis
atopic dermatitis epidemiology genetic polymorphism
2010/11/17
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with an increasing prevalence in industrialized countries. AD belongs to the group of allergic disorders that includes food allergy, alle...
ATOPIC ECZEMA: GENETICS OR ENVIRONMENT?
atopic eczema nonatopic eczema subtypes IgE-associated non-IgE-associated
2010/12/23
Atopic eczema (AE) is a multifactorial skin disease caused by a variety of factors such as genetic conditions, alterated skin structure, immunologic deviations and environmental factors, among others.
Urinary Eosinophil-derived Neurotoxin Concentrations in Patients with Atopic Dermatitis: A Useful Clinical Marker for Disease Activity
atopic dermatitis eosinophil eosinophil-derived neurotoxin visual analogue scale
2010/11/18
Background: It has been reported that measurements of eosinophil-derived neurotoxin (EDN) may be useful for identifying eosinophil activities in allergic diseases including atopic dermatitis.
Methods...
An Improved Mouse Model of Atopic Dermatitis and Suppression of Skin Lesions by an Inhibitor of Tec Family Kinases
allergen atopic dermatitis mite Tec Th2
2010/11/18
We established a highly efficient, highly reproducible protocol to induce skin lesions in NC/Nga mice and successfully applied it to show the efficacy of terreic acid in treating skin lesions. This mo...
Suplatast/Tacrolimus Combination Therapy for Refractory Facial Erythema in Adult Patients with Atopic Dermatitis—A Meta-Analysis Study—
atopic dermatitis erythema meta-analysis suplatast tacrolimus
2010/11/18
Background: Combination of suplatast tosilate with tacrolimus ointment was reported to reduce the dose of tacrolimus ointment with maintained treatment efficacy for refractory facial erythema in atopi...
A Novel Atopic Dermatitis Model Induced by Topical Application with Dermatophagoides Farinae Extract in NC/Nga Mice
animal model atopic dermatitis Dermatophagoides farinae house dust mite NC/Nga mice
2010/11/18
Repeated application of Df extract ointment caused rapid increase in dermatitis scores. Clinical (skin dryness, erythema, edema and erosion) and histological symptoms (dermal and epidermal thickening,...
Dietary Whey Protein Hydrolysate Suppresses Development of Atopic Dermatitis-like Skin Lesions Induced by Mite Antigen in NC/Nga Mice
atopic dermatitis Dermatophagoides pteronyssinus E-selectin mice whey protein
2010/11/18
Background: Oral administration of enzymatic hydrolysate of cow's milk whey protein (WPH) has been reported to produce an anti-inflammatory effect. Since inflammation plays a role in dermatitis of all...
Effect of Home Environment Control on Children with Atopic or Non-atopic Asthma
asthma Der f 1 Der p 1 environment control house dust mites
2010/11/18
Home visit counseling markedly reduced the frequencies of asthma attacks (p < 0.000001), the required theophylline dosages (p < 0.0005), and the levels of HDM allergens (p < 0.0005) in the atopic subg...