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Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet around 70% don’t respond to these medications, which work by removing the “brakes” on the immune system’s response to a...
Researchers at MIT and Dana-Farber Cancer Institute have developed a new way to determine whether individual patients will respond to a specific cancer drug or not. This kind of test could help doctor...
Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy. However, good pharmacolo...
A study by scientists at the University of Arizona and the University of Pittsburgh may hold the key to targeting dormant — or inactive cancer cells, which are resistant to chemotherapy and other tre...
Biomedical engineers at Duke University have discovered a way to detect signs of cancer on a cell-by-cell basis using two lasers and a camera.Several medical devices currently in use and in clinical t...
Interactions between an animal cell and its environment, a fibrous network called the extracellular matrix, play a critical role in cell function, including growth and migration. But less understood i...
Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.Members of Rice’s Cente...
High choline uptake and increased choline kinase activity have been reported in many cancers. This has motivated the use of choline as a biomarker for tumor imaging. Tumors in general are heterogeneou...
The abysmal five year pancreatic cancer survival rate of less than 6% highlights the need for new treatments for this deadly malignancy. Cytotoxic drugs normally target rapidly dividing cancer cells b...
Separating circulating cancer cells from blood cells for diagnostic, prognostic and treatment purposes may become much easier using an acoustic separation method and an inexpensive, disposable chip, a...
A gene normally involved in the regulation of embryonic development can trigger the transition of cells into more mobile types that can spread without regard for the normal biological controls that re...
Breast cancer is one of the leading causes of death in women cancer cases worldwide. Cancer is the result of environmental and genetic factors that contribute to alterations in cellular control, proli...
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
Cell culture and animal studies have demonstrated strong chemopreventative effects of green tea and its associated polyphenols in multiple cancers, though the exact mechanisms of action are not well u...
A team of researchers led by the Whitehead and Broad Institutes has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed n...

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