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Effect of the Combination of Glibenclamide,an ATP-dependent Potassium Channel Blocker, and Metoprolol, a Cardioselective b-adrenoceptor Blocker,During Myocardial Infarction in Conscious Rats
Glibenclamide Metoprolol Arrhythmias Sudden cardiac death Conscious rats
2009/6/29
We investigated the possible interaction of glibenclamide and metoprolol on the occurrence of life threatening arrhythmias during the acute phase of experimental myocardial infarction. Coronary artery...
Simultaneous determination of metoprolol, propranolol and phenol red in samples from rat in situ intestinal perfusion studies
Propranolol Metoprolol Phenol red liquid chromatography Permeability
2010/2/3
Single-pass intestinal perfusion technique (SPIP) is the most used classic technique employed in the study of intestinal absorption of compounds in which a non-absorbable marker such as phenol red is ...