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A 5-year-old girl presented with chronic liver dysfunction. Her serum ceruloplasmin level was within normal range. Urinary copper excretion was slightly elevated. We performed ATP7B gene analysis. And...
Copper is an essential trace metal. Proteins exploit the unique redox nature of this metal to undertake a series of facile electron transfer reactions using copper as a cofactor in a select number of ...
Wilson disease is a genetic disorder of copper metabolism characterized by hepatic and/or neurological manifestations. This disease is caused by mutations in the gene of copper transporting ATPase (AT...
Wilson disease is an autosomal recessive disorder of copper metabolism characterized by hepatic and/or neurological manifestations. This biochemical features of this disease are low serum ceruloplamin...
Wilson disease is an autosomal recessive disorder of copper metabolism. The disease phenotype includes chronic liver disease (cirrhosis), neurological impairment (extra pyramidal signs), Kayser-Fleisc...

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