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Comparative efficacy of caffeic acid phenethyl ester (CAPE), olopatadine hydrochloride, and dexamethasone sodium phosphate in experimental allergic conjunctivitis
Allergic conjunctivitis caffeic acid phenethyl ester dexamethasone sodium phosphate olopatadine hydrochloride
2010/10/14
To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate. Materials and methods: Experimental allergic co...
Evaluation of Novel Scoring System Named 5-5-5 Exacerbation Grading Scale for Allergic Conjunctivitis Disease
allergic conjunctivitis atopic keratoconjunctivitis clinical severity score vernal keratoconjunctivitis
2010/11/16
The median severity scores of the 5-5-5 exacerbation grading scale in VKC, AKC and AC were 243 (range: 12-444), 32.5 (11-344), and 13 (2-33), respectively. The severity score of each ACD disease type ...
Clinical Evaluation of Total IgE in Tears of Patients with Allergic Conjunctivitis Disease Using a Novel Application of the Immunochromatography Method
allergic conjunctivitis disease immunochromatography immunoglobulin E
2010/11/16
The positive ratio obtained by this novel application of the immunochromatography assay was 38 of the 41 in the patients with ACD and none in the 7 controls. IgE indices for the VKC group, AKC group a...
Depletion of Thymus-Derived CD4+CD25+ T Cells Abrogates the Suppressive Effects of α-galactosylceramide Treatment on Experimental Allergic Conjunctivitis
allergic conjunctivitis eosinophils regulatory T cells thymus α-galactosylceramide
2010/11/17
α-GalCer treatment significantly suppressed EC in the thymus-intact mice that had not been treated with anti-CD25 Ab. In contrast, α-GalCer treatment of thymectomized and anti-CD25 Ab-treated mice did...
The Early Efficacy of Topical Levocabastine in Patients with Allergic Conjunctivitis
allergic conjunctivitis artificial tears H1 antagonist histamine levocabastine
2010/11/19
Background: We investigated the early efficacy of topical levocabastine, an H1 histamine-receptor antagonist, in improving the clinical symptoms of allergic conjunctivitis.
Methods: Thirty-six patien...
Efficacy of Levocabastine Hydrochloride Ophthalmic Suspension in the Conjunctival Allergen Challenge Test in Japanese Subjects with Seasonal Allergic Conjunctivitis
allergen challenge test allergic conjunctivitis conjunctival itching levocabastine hydrochloride redness
2010/11/18
The mean itching score in the levocabastine-treated group was 0.08 ± 0.06, which was significantly lower than the mean score of 1.98 ± 0.16 in the vehicle group (P < 0.0001). The redness and chemosis...