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The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion
Indazole-carboxylic acids tolnidamine antispermatogenic agents Sertoli cell
2009/2/23
The indazole-carboxylic acid derivative tolnidamine (TOL) has marked antispermatogenic activity in rats. Previous morphological and biochemical studies indicate that Sertoli cells are one of the tar...
The effects of the indazole carboxylic acid derivative, tolnidamine, on testicular function:I. Early changes in androgen binding protein secretion in the rat
tolnidamine rABP LH FSH testosterone
2009/2/20
The indazole carboxylic acid derivative, tolnidamine, has marked antispermatogenic activity in several animal species. In this study, we assessed the effect of tolnidamine on rat Sertoli cell functi...
Protein secretion by the rat epididymis can be selectively modified in vitro by local anesthetics, glucose deprivation, dinitrophenol, ouabain, and ionophores
Protein secretion rat epididymis selectively modified local anesthetics
2009/2/20
Protein secretion by the caput epididymidis has been examined in vitro using radioactive methionine as a precursor for protein synthesis. Newly synthesized and secreted proteins were separated by gel ...
Obstruction of the vas deferens alters protein secretion by the rat caput epididymidal epithelium in vivo
protein secretion rat caput epididymidal epithelium
2009/2/18
Obstruction of epididymal lumen fluid flow alters the intraluminal environment and potentially changes epididymal epithelial cell function when those functions are dependent on intraluminal regulato...
Androgen binding protein secretion and endocytosis by principal cells in the adult rat epididymis and during postnatal development
Androgen binding protein secretion endocytosis principal cells adult rat epididymis
2009/2/18
Androgen binding protein (ABP) has been shown to be secreted by Sertoli cells and to be actively taken up by the efferent ducts and proximal caput epididymidis and, yet, to be present at high concen...
Secreted products and extracellular matrix from testicular peritubular myoid cells influence androgen-binding protein secretion by Sertoli cells in culture
Cocultures parabiotic cultures dibutyryl cyclic AMP Sertoli cells peritubular myoid cells
2009/2/13
Metabolic cooperation mediated by secreted factors between Sertoli cells and peritubular myoid cells has been well documented. We have confirmed that factors secreted by peritubular myoid cells mo...
Testicular regulation of epididymal protein secretion
Testicular regulation epididymal protein secretion
2009/2/10
The effects of different androgen and testicular fluid levels on the protein synthesis and secretion of the epididymis of mice and rats were examined. In mice, the in vitro protein synthesis and s...