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广州中医药大学医学免疫学课件 抗原antigen目的要求。
The Association between Human Leukocyte Antigen Class II DR3–DQ2 Haplotype and Type 1 Diabetes in Children of the East Azerbaijan State of Iran
Haplotype Genotype HLA-DRB1 HLA-DQB1
2015/11/9
Background: Type 1 diabetes mellitus (T1D) is an autoimmune disease. Several associations between human leukocyte antigen (HLA) complex and T1D were found in various populations. Associations with var...
Antibodies are a family of glycoproteins that bind specifically to foreign molecules (antigens). The binding between antibodies and antigens has high specificity and affinity resulting from various st...
Diagnostic Value of Prostate Specific Antigen and Its Density in Iranian Men with Prostate Cancer
Prostate-specific antigen Density Prostate cancer
2015/9/18
Background: The specific threshold for prostate-specific antigen and density (PSA, PSAD) to delineate which patients are at the highest risk has been controversial. The purpose of this study was to ev...
The in Vitro Effect of Plasmodium berghei Antigen Lysate on Natural Killer (NK) Cell Cytotoxic Activity
Natural killer (NK) cell cytotoxicity Plasmodium berghei
2009/7/2
Plasmodium berghei is the rodent equivalent of Plasmodium falciparum which causes cerebral malaria in humans. However, P. berghei does not cause cerebral malaria in BALB/c mice, instead it leads to pa...
An Immunohistochemical Study of Gastric Neuroendocrine Tumors: Expression of Proliferating Cell Nuclear Antigen and P53 Oncoprotein
Gastric neuroendocrine tumors PCNA p53 oncoprotein
2009/6/30
The aim of this study is to examine expression of Proliferating cell nuclear antigen (PCNA) and p53 oncoprotein in gastric neuroendocrine tumors. 35 gastric neuroendocrine tumors were analyzed for fir...
Expression of Fas Antigen and Bcl-2 Protein in Liver Tissues of Patients with Chronic Hepatitis B
Fas antigen Bcl-2 protein chronic hepatitis B
2009/6/29
The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a ...
Immunization of Mice with Plasmid DNA Encoding Hepatitis B Virus Core Antigen (HBcAg)
Hepatitis B virus core antigen DNA immunization
2009/6/25
The aim of this study was to investigate the antibody response following immunization with plasmid vector DNA containing the hepatitis B virus core antigen (HBcAg) gene of a hepatitis B virus (HBV) is...
Development of a Highly Sensitive ELISA for Quantification of Hepatitis B Virus (HBV) Surface Antigen (HBsAg)
HBsAg monoclonal antibody ELISA
2009/6/17
Background: Hepatitis B Virus (HBV) infection is of global importance and many studies are aimed to develop more sensitive diagnostic tools and improve therapeutic options. HBV infection is diagnosed ...
Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice
aged mouse immunosuppression phospholipase A2 restraint stress specific antibody
2010/11/16
Background: We have recently found that exposure to acute restraint stress suppresses antigen-specific antibody production, including IgE, in a murine model of allergic rhinitis. Although age-related ...
Evaluation of Adjuvant Activities Using Human Antigen Presenting Cells in Vitro
adjuvant cAMP dendritic cells Notch ligand THP-1
2010/11/17
Background: Immunomodulators such as lipopolysaccharides (LPS) and forskolin change the nature of dendritic cells (DCs) to induce Th1 and Th2 cells, respectively, thereby designated Th1 or Th2 adjuvan...
Development of Single Chain Antibodies to P185 Tumor Antigen
scFv Human recombinant antibody P185 Cancer immunotherapy
2015/9/15
Background: The human heavy (VH) and light (VL) chain variable genes are amplified and randomly assembled together and cloned into the minor coat protein gene (g3p) of M13 bacteriophage. The resulting...
山东临朐胃癌高发人群和北京人群Lewis血型抗原相关SE基因多态性分析Analysis of Polymorphisms on Lewis Blood Group Antigen Related SE Gene in the Populations in Shandong with High-risk of Gastric Cancer and Beijing
胃癌 Lewis血型抗原 SECRETOR基因 基因多态性
2007/12/30
摘要为探讨宿主的遗传背景和幽门螺杆菌(Helicobacter pylori,H.pylori)相关胃癌的易感性之间的关系,本文采用PCR产物直接测序和PCR-RFLP的方法,检测142例山东临朐县胃癌高发人群个体(包括69例癌症患者和73例非癌个体)和93例北京正常对照个体SE基因多态性的分布特点。结果显示:sew/sew基因型在山东非癌个体和北京人群之间的分布差异具有统计学意义(P<0.01,...
Detection of Mycobacterial antigen and antibody in
Tuberculosis PPD Antituberculous antibody Reverse passive hemagglutination
2015/9/9
Background: Little is known about changes in total antibodies occurring during the progression of tuberculosis or its treatment. Using passive and reverse passive hemagglutination methods, mycobacteri...