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分析 Lung VCAR软件测量不同剂量条件下MSCT图像中模拟肺小结节的准确度。方法 猪心肺联合器官7个,膨胀猪肺后注入动物脂肪、石蜡、碘化油混合物,制备成模拟肺小结节模型,肺周围包绕水囊模拟胸廓。在10、15、20、25、30、35、40、45、50、60、70、80、90及200 mA不同管电流下进行MSCT扫描,原始数据用1.25 mm骨重建,获得薄层数据导入AW 4.4工作站,用Lung...
An Investigation on Adherence of Cryptococcus neoformans Serotypes (A,B,C and D) in Rat Lung Cell Culture
Cryptococcus neoformans serotype adherence cell culture
2009/7/6
Cryptococcus neoformans causes an opportunistic infection known as cryptococcosis principally in immunocompromised individuals. It is not clearly known whether the serotype of the infecting strain of ...
Angiotensin Converting Enzyme Activity in the Serum, Lung, Liver and Kidney in Streptozotocin -Induced Diabetic Rats and Diabetic Nephropathy
Angiotensin Converting Enzyme Streptozotocin-Diabetes Nephropathy
2009/7/2
To clarify the relationship between the alterations of the levels of angiotensin converting enzyme (ACE) and diabetic nephropathy, ACE activity in the lung, liver, kid-ney and serum were investigated ...
The Role of Serum on the Adhesion of Cultured Chinese Hamster Lung (CHL) Cells
CHL Cells dhesion strength serum proteins
2009/7/2
The roles of serum on the initial attachment and adhesion strength of CHL cells, which is gained following initial attachment, spreading and growth, on tissue culture polystyrene dish were determined ...
Lead may exert toxic effects on several organ systems, but those in the lung are the most insidious. Therefore the aim of the present study was to investigate the morphological alterations caused by l...
The Role of Pr otein Synthesis in the Adhesion of Chinese Hamster Lung Cells
Lung Cells Adhesion Synthesis
2009/6/30
In order to determine the effect of endogenous protein synthesis on CHL cell adhesion, the initial attachment of these cells to tissue culture dishes was measur ed in the pr esence of 1µgml -1 e...
The Effect of Sulfur Dioxide on t-Butyl Hydroperoxide Induced Oxidative Stress in Lung Tissues of Rats
Chemiluminescence SO2 lung ageing rat
2009/6/29
In this study, the effects of sulfur dioxide (SO2) ,a common pollutant in urban air, on t-butyl hydroperoxide-induced oxidative stress in rat lung tissues were examined. Ten young rats and 10 adult r...
A Preliminary Study of DNA Damage in Peripheral Lymphocytes from Lung Cancer Patients and Healthy Subjects
Comet assay DNA damage Lung cancer Lymphocyte
2009/6/24
A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung ca...
南京汉族群体肺癌易感性相关基因的研究Studies of the Genes Related to Lung Cancer Susceptibility in Nanjing Han Population, China
肺癌 代谢酶基因 多态性 遗传易感性
2008/1/8
摘要
为了探讨南京汉族群体肺癌易感性相关基因，我们采用1:1病例对照研究方法，以PCR—RFLP技术检测了152对肺癌和健康对照的CYP1A1、CYP2E1、GSTM1、GSTT1、GSTP1、mEH和NQO1基因的基因型并分析其与肺癌的相关性。结果发现携带CYP1A1突变基因型（wt/mt和mt/mt）的个体明显增加患肺鳞癌的风险(OR=2.31,95%CI=1.23-4.36)；GSTT1（...
Interleukin-4 and interleukin-13 induce fibronectin production by human lung fibroblasts
fibronectin human lung fibroblast interleukin-4 interleukin-13 remodeling
2010/11/25
The results showed that IL-4 and IL-13 induced fibronectin production in a time- and a concentration-dependent manner. Anti-transforming growth factor (TGF)-β1 antibody (ab) inhibited TGF-β1-induced f...
Effects of Th2 cytokines and eosinophils on stem cell factor production by lung fibroblasts
eosinophil fibroblast interleukin-4 interleukin-5 stem cell factor
2010/11/24
Interleukin-4 significantly enhanced SCF production, whereas tumor necrosis factor-α, interferon-γ and IL-1α showed suppressive effects on SCF pro-duction. When fibroblasts were cultured with IL-4 plu...
Disposition of Alpha-1-Antitrypsin in the Isolate Perfused Rabbit Lung
Alpha-1-Proteinase Inhibitor Pulmonary absorption Isolated perfused rabbit lung
2010/4/29
The potential for delivering large molecular weight proteins into the lungs to reach local or systemic sites of action was investigated by examining the disposition of alpha-1-antitrypsin in the isola...