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2017哮喘 Keystone Symposia（2017 Keystone Symposia on Asthma: From Pathway Biology to Precision Therapeutics）
Asthma Pathway Biology
2017/1/17
The meeting will begin on Sunday, February 12 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 16 with a closing plenary ...
Correlation between the Prostaglandin D2/E2 Ratio in Nasal Polyps and the Recalcitrant Pathophysiology of Chronic Rhinosinusitis Associated with Bronchial Asthma
aspirin-intolerant asthma bronchial asthma chronic rhinosinusitis prostaglandin D2 prostaglandin E2
2010/11/17
The concentrations of PGD2 were significantly higher in the nasal polyps of the CRS-ATA group. The concentrations of PGE2 were lowest in the nasal polyps of the CRS-AIA group. The PGD2/PGE2 ratio was ...
Role of Prostaglandin D2 and Its Receptors in the Pathophysiology of Asthma
asthma CRTH2 DP eosinophils lipid mediators single nucleotide polymorphisms
2010/11/17
Prostaglandin D2 (PGD2) is one of the most abundant lipid mediators present in the airways of asthmatics. However, little was known of the role it plays in the pathophysiology of asthma, until the ide...
Low Magnesium Concentration in Erythrocytes of Children with Acute Asthma
Asthma Children Magnesium
2010/2/3
Magnesium (Mg) is the second most abundant intracellular cation and is involved in numerous physiological functions, including protein folding, intracellular signaling and enzyme catalysis. It has bee...
Air Pollution Induced Asthma and Alterations in Cytokine Patterns
Air Pollution Asthma Cytokines
2010/2/4
In recent decades, clinicians and scientists have witnessed a significant increase in the prevalence of allergic rhinitis and asthma. The factors underlying this phenomenon are clearly complex; howeve...
Advances in the pathophysiology of bronchial asthma
apoptosis bronchial asthma eosinophils Fas ligand GATA-3 inflammation STAT6 T cells Th2 cytokines
2010/11/25
Asthma is a complex disorder associated with the activation of T lymphocytes and with eosinophil infiltration within the airways. A substantial amount of current research involves the interaction amon...
Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology
β-adrenergic receptor agonists anti-IgE antibody anti-interleukin-5 monoclonal antibody asthma corticosteroids leukotriene inhibitors theophylline
2010/11/24
The mainstay of chronic asthma management consists of using pharmacological agents that induce broncho-dilatation, such as short-acting β-adrenergic receptor agonists (bronchodilators or relievers), a...
Pathological and radiological approach to the small airway disease in asthma: Limitation of current inhaled corticosteroid therapy
asthma eosinophil high-resolution computed tomography inhaled corticosteroid small airway
2010/11/22
The small airway disease in asthma is characterized by airway wall thickening associated with eosinophilic inflammation and hypervascularity. In our study, predicted forced expiratory volume in 1 s (%...
Association of Tumor Necrosis Factor-α and Neutrophilic Inflammation in Severe Asthma
myeloperoxidase neutrophilic inflammation neutrophils severe asthma tumor necrosis factor-α
2010/11/22
The concentration of TNF-α was not correlated with neutrophils in healthy controls or mild asthma patients. In sputum from severe asthma patients, however, the concentration of TNF-α is significantly ...
Effect of Transdermal Tulobuterol Added to Inhaled Corticosteroids in Asthma Patients
bronchial asthma long-acting β2-agonist transdermal therapeutic system tulobuterol tape
2010/11/22
In patients with persistent asthma who require inhaled short-acting β2-agonists while receiving inhaled corticosteroids, transdermal tulobuterol significantly improved PEF in a dose-dependent manner, ...