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上调miR-181a抑制香烟提取物诱导的支气管上皮细胞致炎因子生成与collagen IV、fibronectin和α-SMA表达
微小RNA-181a 慢性阻塞性肺疾病 气道炎症 气道重塑 NF-κB/TGF-β1/Smad3信号通路
2020/9/11
探讨微小RNA-181a（miR-181a）对香烟提取物（cigarette smoke extract，CSE）诱导的人支气管上皮细胞（human bronchial epithelial cells， HBECs）致炎因子生成与IV型胶原蛋白（collagen IV）、纤连蛋白（fibronectin）和α-平滑肌肌动蛋白（α-SMA）表达的影响，并分析其可能的机制。方法：RT-qPCR检测C...
Fibronectin差别黏附法筛选、纯化软骨终板干细胞
纤维连接蛋白 软骨终板干细胞 差别黏附筛选法
2013/11/15
通过Fibronectin介导进行差别黏附筛选软骨终板干细胞，观察筛选的效果及其初步生物学性能。 方法 从脊柱融合术中获取椎间盘软骨终板标本，机械-酶消化法获取原代软骨终板细胞，体外扩增至第2代后接种于Fibronectin包被过的培养瓶,孵育20 min后将未贴壁细胞及培养液转移至新培养瓶再孵育40 min, 吸弃未贴壁细胞及培养液，所得2瓶细胞进行体外扩增，流式细胞仪检...
Involvement of Fibronectin and Matrix Metalloproteinases in Airway Smooth Muscle Cell Migration for the Process of Airway Remodeling
airway remodeling cell migration fibronectin matrix metalloproteinases smooth muscle cells
2010/11/12
The response of bSMC migration to bSMC-conditioned medium increased with time in culture, and fibronectin (FIB) was detected as a chemoattractant for bSMCs in bSMC-conditioned medium by western blot a...
Plasma Fibronectin and Urine Glycosaminoglycane Levels in Rheumatic Diseases
Rheumatic disease fibronectin glycosaminoglycane
2009/7/2
In this study, plasma fibronectin and urine glycosaminoglycane levels were determined spectrophotometrically in 20 Rheumatoid arthritis, 10 Ankilosing spondilites, 22 osteoarthrosis and 21 healthy con...
The Importance of Fibronectin,Haptoglobin,Ceruloplasmin and Transferrin in the Early Diagnosis of Neonatal Sepsis
Neonatal sepsis fibronectin haptoglobin ceruloplasmin transferrin
2009/6/30
Serum fibronectin, haptoglobin, ceruloplasmin, and transferrin concentrations were measured in 44 term neonates with culture proven sepsis and a control group of 37 normal neonates of similar age, sex...
Clinical and experimental studies on fibronectin in bronchial asthma
bronchial asthma eosinophil adherence eosinophil chemotaxis eosinophils fibronectin
2010/11/24
Background: Clinical and experimental studies were performed to investigate the kinetics of fibronectin (FN) and its clinical significance in bronchial asthma.
Methods: Measurements of plasma fibrone...