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探讨尼美舒利对喉鳞状细胞癌裸鼠皮下移植模型的抑瘤作用及机制。方法建立人喉鳞癌Hep-2细胞株裸鼠移植瘤模型，应用尼美舒利处理裸鼠，观察肿瘤生长情况并绘制生长曲线，免疫组织化学技术检测移植瘤组织中COX-2、CD44和MMP-7蛋白表达，RT-PCR技术检测移植瘤组织中COX-2、CD44 和MMP-7mRNA表达情况。结果与对照组相比，治疗组肿瘤体积增长较对照组慢，体积抑瘤率为63.36%，重量抑...
CD44 on blood eosinophils as a novel marker of bronchial asthma management
bronchial asthma CD44 eosinophils flow cytometry
2010/11/29
Bronchial asthma (BA) is characterized by infiltration of the respiratory tracts by eosinophils. A wide variety of adhesion molecules is involved in the binding of eosinophils to the vascular endothel...