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Suppression of steroid receptor-chromatin interaction by inhibitors present in ammonium sulfate-fractionated rat testicular androgen receptor preparations
steroid receptor-chromatin interaction inhibitors present ammonium sulfate-fractionated rat
2009/2/23
Tritiated androgen receptor complex was partially purified by ammonium sulfate precipitation at 15 to 37% saturation from rat testicular or prostatic cytosols. A greater amount of prostatic tritiate...
Evidence for age-dependent changes in Sertoli cell androgen receptor concentration
age-dependent changes Sertoli cell receptor concentration
2009/2/23
Cytosol and nuclear receptor concentrations in Sertoli cells isolated from the testes of 15-, 25-, and 35-day-old rats were measured using hydroxylapatite separation procedures. In these cells the m...
Androgen receptor levels and androgen contents in the prostate lobes of intact and testosterone-treated Noble rats
Androgen receptor levels androgen contents prostate lobes testosterone-treated Noble rats
2009/2/23
Plasma testosterone (T) levels were correlated with androgen receptors, tissue content of T, and 5 alpha-dihydrotestosterone (DHT) in the three anatomically-discrete prostate lobes of intact and cas...
Characterization of a TPA-response element in the 5'-flanking region of the androgen receptor gene
Steroid receptor gene expression phorbol esters
2009/2/18
The androgen receptor (AR) protein is an important transacting factor that is necessary for mediating gene expression of androgen-responsive genes. The expression of the AR gene is regulated by an...
The effects of spinal cord injury on the status of messenger ribonucleic acid for TRPM 2 and androgen receptor in the prostate of the rat
spinal cord messenger ribonucleic TRPM 2 rat
2009/2/17
The prostate is one of the male accessory sex glands that produce fluid components of the seminal plasma. In addition to androgen, a normal innervation of the prostate is believed to be important ...
Androgen receptor immunoexpression in the testes of subfertile men
Androgen receptor immunoexpression subfertile men
2009/2/13
The localization and intensity of androgen receptor immunostaining was studied in the testes of 37 subfertile men with oligozoospermia and normal serum gonadotropin levels using a polyclonal antib...
Cloning and partial sequence of the rabbit androgen receptor：expression in fetal urogenital tissues
Development mesonephros androgen receptor urogenital sinus rabbit prostate
2009/2/13
Genetic studies indicate that the actions of testosterone and dihydrotestosterone are mediated by a single androgen receptor (AR). The basis for the differential effects of these hormones during d...
Localization of androgen receptor and cell-specific cytokeratins in basal cells of rat ventral prostate
androgen receptor cell-specific cytokeratins basal cells rat ventral prostate
2009/2/13
Immunocytochemical techniques labeled androgen receptor and cell-specific cytokeratins in the basal cells of rat ventral prostate. In addition, nonradioactive in situ hybridization verified the prod...
Modulation of androgen receptor transcriptional activity by the estrogen receptor
Androgen receptor estrogen receptor modulation transcription 016 cells GC cells
2009/2/12
Estrogen/androgen receptor interactions in naturally occurring physiological systems and the effect of their respective steroid hormones on transcriptional activity remain undefined. In an attempt...
Human androgen receptor binding to the androgen response element of prostate specific antigen
Human androgen receptor androgen response element prostate specific antigen
2009/2/12
This study examined the in vitro interaction of the human androgen receptor with a putative androgen response element (ARE) in the promoter region of the prostate specific antigen (PSA) gene. To cha...
Insulin-like growth factor 1, but not growth hormone, has in vitro proliferative effects on neonatal foreskin fibroblasts without affecting 5-alpha-reductase or androgen receptor activity
5-a-Reductase androgen receptor micropenis
2009/2/11
Clinical observation of patients with congenital growth hormone (GH) deficiency and Laron-type dwarfism suggests that factors such as GH or insulin-like growth factor 1 (IGF-1) might in addition to ...
Nuclear androgen receptor dynamics in testicular peritubular and Sertoli cells
Androgen receptor testis Sertoli cells peritubular
2009/2/6
Nuclear androgen receptor dynamics were analyzed in peritubular cells and compared with those in cultured Sertoli cells. Nuclear receptors with a high affinity for [3H]dimethylnortestosterone (DMN...
Characterization and partial purification of the 8-9S androgen receptor from benign prostatic hyperplasia tissues
androgen receptor human prostate benign prostatic hyperplasia
2009/1/5
The present study reports a 3,800-fold purification of the 8-9S androgen-receptor complex from benign prostate hyperplasia (BPH) tissues using differential chromatography. In addition, the BPH androge...
CAG repeat length analysis and mutation screening of the androgen receptor gene in Japanese men with idiopathic azoospermia
Male infertility Kennedy disease sperm production
2008/12/29
Because androgens are required for normal spermatogenesis, we are investigating abnormalities in the androgen receptor as a possible cause of impaired spermatogenesis in patients with idiopathic mal...
Androgen receptor regulation of G1 cyclin and cyclin-dependent kinase function in the CWR22 human prostate cancer xenograft
Androgen receptor regulation G1 cyclin cyclin-dependent kinase CWR22 huma prostate cancer
2008/12/29
Human prostate cancer is initially dependent on androgens for growth, and androgen-dependent cells undergo apoptosis after castration. However, a subset of androgen-responsive cells survives and event...