搜索结果: 1-5 共查到“性科学 pharmacokinetics”相关记录5条 . 查询时间(0.062 秒)
Pharmacokinetics of 7 alpha-methyl-19-nortestosterone in men and cynomolgus monkeys
MCR SHBG replacement therapy male
2009/2/17
Testosterone and its esters are widely used for androgen replacement therapy. In the prostate, testosterone ins 5 alpha-reduced to dihydrotestosterone (DHT), which leads to an amplification of its...
Pharmacokinetics and pharmacodynamics of a parenteral testosterone microsphere formulation in the male rat. Demonstration of dose dependence and controlled release
Testosterone microsphere formulation androgen delivery methods testosterone effects on LH, FSH, and accessory sex organs rat
2009/2/11
This study examined the pharmacokinetics (the time course and pattern of testosterone release) and pharmacodynamics (effects on accessory sex organ weights, and serum LH and FSH levels) of a biode...
Pharmacokinetics of Testosterone Undecanoate Injected Alone or in Combination With Norethisterone Enanthate in Healthy Men
Azoospermia oligozoospermia male contraception
2008/12/24
Long-acting injectable testosterone undecanoate (TU) is a promising androgen for male hormonal contraception. As a prerequisite for a planned multicenter male contraceptive efficacy study, we studie...
Pharmacokinetics and Degree of Aromatization Rather Than Total Dose of Different Preparations Determine the Effects of Testosterone：A Nonhuman Primate Study in Macaca fascicularis
Spermatogenesis testis male contraception clinical chemistry primates
2008/12/19
Currently available testosterone (T) preparations differ substantially in their pharmacokinetic profile that might influence their androgenic properties in terms of suppression of the gonadal axis, ef...
Oral Testosterone-Triglyceride Conjugate in Rabbits：Single-Dose Pharmacokinetics and Comparison With Oral Testosterone Undecanoate
Hypogonadism androgen lymphatics
2008/12/19
Development of a safe and effective oral form of testosterone has been inhibited by the rapid hepatic metabolism of nonalkylated androgens. Since triglycerides are absorbed via lymphatics and bypass...