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Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage?
Tomato lycopene carotenoids
2016/5/31
Lycopene, the main carotenoid in tomato, has
been shown to be a potent antioxidant in vitro. However, there is
no significant evidence of its antioxidant action in vivo.
Watercress supplementation in diet reduces lymphocyte DNA damage and alters blood antioxidant status in healthy adults1,2,3
Watercress cruciferous vegetables DNA damage antioxidants humans cancer biomarkers
2008/12/9
Background: Cruciferous vegetable (CV) consumption is associated with a reduced risk of several cancers in epidemiologic studies.Objective: The aim of this study was to determine the effects of waterc...
Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial [ISRCTN68505294]
antioxidant parameters blood DNA
2008/4/23
Red wine (RW) is rich in antioxidant polyphenols that might protect from oxidative stress related diseases, such as cardiovascular disease and cancer. Antioxidant effects after single ingestion of RW ...
Oxidative DNA damage in human white blood cells in dietary antioxidant intervention studies
Antioxidants comet assay humans intervention studies 7-hydroxy-8-oxo-2′-deoxyguanosine oxidative DNA damage vitamin C vitamin E carotenoids
2016/12/19
Many epidemiologic studies have addressed the possible preventive effects of antioxidants in disease causation and progression. With the use of molecular techniques, it is feasible to investigate spec...
Why and how should we measure oxidative DNA damage in nutritional studies? How far have we come?
oxidative DNA nutritional studies
2016/6/8
Free radicals and other reactive species are constantly
generated in vivo and cause oxidative damage to DNA at
a rate that is probably a significant contributor to the age-related
development of ca...
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
DNA methylation genomic DNA folate homocysteine humans elderly women
2016/6/8
Background: Methylation of genomic DNA is dependent on an
adequate supply of folate coenzymes. Previous data support the
hypothesis that abnormal DNA methylation plays an integral
role in carcinoge...
Folate, DNA methylation, and gene expression: factors of nature and nurture
nature and nurture nature and nurture
2016/6/8
Folate provides the one-carbon units required for purine and
thymidylate syntheses and for methylation of a wide variety of
essential biological substances, including phospholipids, proteins,
DNA, ...