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The Food and Nutrition Board of the National Academy of Sciences states that 95 g vitamin D/d is the lowest observed adverse effect level (LOAEL).
Background: In a previous 2-y randomized controlled trial, we showed that calcium- and vitamin D3–fortified milk stopped or slowed bone loss at several clinically relevant skeletal sites in older me...
Background: Vitamin D3 may have therapeutic potential in several diseases, including multiple sclerosis. High doses of vitamin D3 may be required for therapeutic efficacy, and yet tolerability—in the ...
For adults, vitamin D intake of 100 mcg (4000 IU)/day is physiologic and safe. The adequate intake (AI) for older adults is 15 mcg (600 IU)/day, but there has been no report focusing on use of this do...
Low serum 25 hydroxyvitamin D3 (vitamin D3) is known to perturb cellular function in many tissues, including the endocrine pancreas, which are involved in obesity and type II diabetes mellitus (TIIDM)...
Neither the efficiency of the 25-hydroxylation of vitamin D nor the steady state relation between vitamin D3 and 25-hydroxyvitamin D [25(OH)D] has been studied in humans.

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