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RNA nanoparticle therapy stops the spread of incurable bone marrow cancer（图）
RNA 纳米颗粒疗法 骨髓癌 肿瘤治疗
2023/6/27
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body’s wound healing response to various forms of da...
Study:Changing the environment within bone marrow alters blood cell development
Changing the environment bone marrow blood cell development
2017/3/14
Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.The findings, reported in th...
Plasma antioxidant status after high-dose chemotherapy: a randomized trial of parenteral nutrition in bone marrow transplantation patients
Parenteral nutrition antioxidants glutathione, bone marrow transplantation cysteine
2016/6/7
Background: Chemotherapy and radiation therapy result in
increased free radical formation and depletion of tissue antioxidants.
It is not known whether parenteral nutrition (PN) administered
during...
The Impact of Family Functioning on Children's Adaptation During a Parent's Bone Marrow Transplantation
adaptation parental illness bone marrow transplant
2015/1/19
Bone marrow transplant (BMT) is being used ever more widely for advanced and refractory malignancies. The family unit and individual members are profoundly affected by this treatment process. Few stud...
Engraftment of bone marrow-derived cells after nonlethal radiation in syngeneic C57BL/6 mice
Chimerism Bone marrow-derived cells Nonlethal radiation
2015/11/24
To study the characteristics of cell engraftment in mice at a lower dose under nonlethal radiated condition.Methods A syngeneic C57BL/6 mouse model, transplanted with 1×107 bone marrow cells and expos...
Th Roles of Notch1 and PKC-Θ in Immune Mediated Bone Marrow Failure
Roles of Notch1 PKC-Θ Immune Mediated Bone Marrow Failure
2014/10/23
We sought to evaluate the individual contributions of Notch1 and PKC-ζ to disease progression in a mouse model of immune-mediated bone marrow failure and to define a mechanism for their potential cell...
Nmp4 restricts bone marrow osteoprogenitors and parathyroid hormone induced bone formation in healthy and estrogen depleted female mice
Osteoprogenitor Estrogen depletion
2015/5/21
We have shown that nuclear matrix protein 4 (Nmp4) attenuates the response to intermittent parathyroid hormone (PTH) in healthy and ovariectomized (OVX) female mice using a global knockout of the Nmp4...
Effects of Capsaicin on Adipogenic Differentiation in Bovine Bone Marrow Mesenchymal Stem Cell
Bovine Bone Marrow Mesenchymal Stem Cells [BMSCs] Capsaicin Adipogenesis Differentiation Apoptosis
2016/5/17
Capsaicin is a major constituent of hot chili peppers that influences lipid metabolism in animals. In this study, we explored the effects of capsaicin on adipogenic differentiation of bovine bone marr...
Tissue Engineering Using Human Mineralized Bone Xenograft and Bone Marrow Mesenchymal Stem Cells Allograft in Healing of Tibial Fracture of Experimental Rabbit Model
Bone Xenograft Allograft Mesenchymal stem cells Healing Rabbit
2015/9/25
Background: Bone healing and its reconstruction in fractures, especially in long bones are of particular importance in regenerative medicine. This study compares the bone healing rate after a human xe...
Removing Financial Barriers to Organ and Bone Marrow Donation: The Effect of Leave and Tax Legislation in the U.S.
incentives altruism organ donation bone marrow donation
2012/10/22
In an attempt to alleviate the shortfall in organs and bone marrow available for transplants, many U.S. states passed legislation providing leave to organ and bone marrow donors and/or tax benefits fo...
Detection of Aspergillus by Nested Assay in Bone Marrow Transplantation (BMT) Patients
Aspergillus Nested Assay Bone Marrow Transplantation (BMT) Patients
2015/9/23
The increasing incidence of aspergillosis emphasizes to improve the diagnostic tools.1 Aspergillus fumigatus is associated with a high rate of mortality among patients receiving Bone Marrow Transplant...
Comparison of Proliferation,Senescence and Differentiation into Skeletal Cell Lineages of Murine Bone Marrow-Derived and Amniotic Fluid Mesenchymal Stem Cells
Amniotic fluid Bone marrow Mesenchymal stem cells Proliferation Differentiation
2015/9/21
Background: While mesenchymal stem cells (MSCs) have been isolated from multiple tissue sources, the differences existed between the cells from different tissues have still remained to be clarified. T...
The effect of microorganisms on cytokine secretion from bone marrow dendritic cells
Dendritic cells microorganisms cytokines
2010/10/14
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial ...
Burnout at a bone marrow transplantation unit in Turkey: Effects of interactive psychoeducational seminars
Bone marrow transplantation unit burnout health staff psychoeducation
2010/1/11
Aim: Health staff working at bone marrow transplantation units (BMTUs) is found to be at a higher risk for suffering from burnout. This paper reports a critical assessment of how burnout level of the ...