搜索结果: 1-15 共查到“Genome”相关记录289条 . 查询时间(0.113 秒)
最近，西湖大学施红军团队在Genome Medicine杂志上发表了题为 ENU-based dominant genetic screen identifies contractile and neuronal gene mutations in congenital heart disease 的最新研究成果。该研究进行了迄今为止最大规模的小鼠先心病正向显性遗传筛查。通过筛选一万多例小鼠心脏，...
全世界有数十万份小麦种质资源保存在基因库中，且小麦新审定品种数量逐年增加。对小麦种质资源精准基因分型是解锁遗传多样性、加速品种改良的首要步骤。然而，现有的分子标记检测技术仍然具有检测通量低、成本偏高、技术复杂、敏感性偏低等问题。目前，仍缺乏面向育种应用的高通量、低成本的小麦种质材料的基因型鉴定技术。
2024年6月11日，中国农业科学院深圳农业基因组研究所李奎教授主编的家畜基因组编辑英文专著《Livestock Genome Editing Tools》由Elsevier旗下的Academic Press出版社出版。该书汇集了当前国内外家畜基因编辑领域最前沿的研究成果和实用技术，填补了全球农业大型动物基因组编辑领域英文专著的空白。
《Archives of Virology》 期刊 —— Complete genome sequence of a novel partitivirus with a dsRNA3 segment, isolated from Fusarium commune strain CP-SX-3 causing strawberry root rot（图）
镰刀菌 真菌病毒 种类 多样性
2024/6/14
近日，辽宁省果树科学研究所植保课题赵雨萌实习研究员为第一作者，在《Archives of Virology》发表了题为《Complete genome sequence of a novel partitivirus with a dsRNA3 segment, isolated from Fusarium commune strain CP-SX-3 causing strawberry roo...
2024年1月8日，良渚实验室沈宁研究员、伍赛教授，博士生刘逸程、张天韵等在Genome Medicine上发表了题为MAGPIE: accurate pathogenic prediction for multiple variant types using machine learning approach的研究论文，报道了使用多模态数据注释对多类型变异进行致病性预测的算法框架MAGPIE（M...
pssRNAit-a web server for designing effective and specific plant siRNAs with genome-wide off-target assessment
Bioinformatics plant RNAi siRNA efficacy off-target gene silencing VIGS syntasiRNA
2024/1/12
We report an advanced web server named pssRNAit (plant specific small non-coding RNAi tool) that can be used to design a pool of small interfering RNAs (siRNAs) for highly effective, specific, and non...
Unraveling the 3D Genome Architecture in Plants: Present and Future
3D genomic methods plant 3D genome dynamic chromatin organization liquid-liquid phase separation RNA-chromatin interaction
2023/12/19
The eukaryotic genome has a hierarchical three-dimensional organization with functional implications in DNA replication, DNA repair, and transcriptional regulation. Over the past decade, scientists ha...
Genome-wide analysis of the AREB/ABF gene lineage in land plants and functional analysis of TaABF3 in Arabidopsis
ABFs Land plants Phylogenetic relationship Expression analysis TaABFs Drought stress
2023/12/15
Previous studies have shown that ABFs (abscisic acid-responsive transcription factors) are important ABA-signaling components that participate in abiotic stress response. However, little is known abou...
Genome-wide analysis and expression profile of the bZIP gene family in poplar
Poplar bZIP gene family Tissue-differential expression Salt stress Co-expression analysis
2023/12/8
The bZIP gene family, which is widely present in plants, participates in varied biological processes including growth and development and stress responses. How do the genes regulate such biological pr...
MYB transcription factor family in sweet cherry (Prunus avium L.): genome-wide investigation, evolution, structure, characterization and expression patterns
MYB transcription factors PavMYB genes Phylogenetic analysis Expression pattern Dormancy
2023/11/30
MYB Transcription factors (TFs) are most imperative and largest gene family in plants, which participate in development, metabolism, defense, differentiation and stress response. The MYB TFs has been ...
Functional divergence of Populus MYB158 and MYB189 gene pair created by whole genome duplication
duplicate gene functional divergence MYB transcription factor regulatory networks secondary cell wall biosynthesis whole genome duplication
2023/11/28
Whole genome duplication (WGD) provides new genetic material for genome evolution. After a WGD event, some duplicates are lost, while other duplicates still persist and evolve diverse functions. A par...
Targeted introduction of heritable point mutations into the plant mitochondrial genome
plant mitochondrial genome heritable ALEN-GDM mtDNA genome editing CRISPR-Cas
2023/11/28
The development of technologies for the genetic manipulation of mitochondrial genomes remains a major challenge. Here we report a method for the targeted introduction of mutations into plant mitochond...
中国人民大学统计学院李扬教授及学生在期刊Genome Biology发表论文（图）
李扬 数据分析 生物统计
2024/11/26
中国人民大学统计学院李扬教授及博士生吴明聪在《Genome Biology》发表论文，提出基于混合零膨胀负二项模型的单细胞数据聚类分析方法，能够有效控制表达数据中的技术脱落及批次混杂问题，并创新性地利用惩罚技术实现同步的高度变异基因识别，是探索细胞间的异质性及与异质性机制形成相关的基因表达研究的有力工具。研究结果显示，该方法在异质性和基因识别方面均具有一定优势。
The genome of homosporous maidenhair fern sheds light on the euphyllophyte evolution and defences
Adiantum capillus-veneris evolution of seed plants origin of euphyllophytes defences
2023/11/16
Euphyllophytes encompass almost all extant plants, including two sister clades, ferns and seed plants. Decoding genomes of ferns is the key to deep insight into the origin of euphyllophytes and the ev...
植物基因组学与新绿色革命论坛：Atypical disease resistance genes across the genome of wheat（2023.10.23日10:00）
植物基因组学 新绿色革命 麦类作物
2023/10/28
植物基因组学与新绿色革命论坛：Atypical disease resistance genes across the genome of wheat（2023.10.23日10:00）。