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Effects of gadolinium and other metal on the neurotoxicity of immortalized hypothalamic neurons induced by zinc
zinc GT1-7 gadolinium aluminum apoptosis
2009/4/1
Zinc is an essential trace element and crucial for numerous biological functions. In contrast, excessive zinc in the synapses plays central roles in the neurodegenerative processes following brain inj...
Aluminum and Human Health: Its Intake, Bioavailability and Neurotoxicity
bioavailability gastrointestinal absorption contamination apoptosis
2009/3/16
Aluminum is the most abundant metal in the earth's crust. However, it is not essential for life. Owing to its specific chemical properties, aluminum inhibits more than 200 biologically important funct...
Neurotoxicity of aluminum hydroxyl polymer on primary cultured neurons of rat cerebral cortex
chemical speciation culture Alzheimer's disease
2009/3/16
Aluminum(Al)is the 3rd most abundant on the earth. However, it is not essential and harmful to life beings. Al has been suspected to have a relation with various neurodegenerative diseases. The increa...
Neurotoxicity of Trace Elements and the Pathogenesis of Senile-Type Dementia
Apoptosis Ca homeostasis cultured neuron Alzheimer's disease vascular dementia
2009/3/16
Both the deficiency and the excess of trace elements can severely damage of the central nervous system. In particular, recent studies have suggested the implication of aluminum and zinc in the pathoge...
Neurotoxicity of Zinc：The Involvement of Calcium Homeostasis and Carnosin
Calcium homeostasis vascular type of dementia ischemia excite toxicity
2009/3/16
Zinc is an essential trace element that is abundantly present in the brain. In spite of its importance for normal brain functions, it is widely recognized that excess zinc is neurotoxic. Numerous stud...
EVALUATION OF NEUROTOXICITY OF REPEATED DERMAL APPLICATION OF CHLORPYRIFOS ON HIPPOCAMPUS OF ADULT MICE
dermal toxicity chlorpyrifos repeated exposure cholinesterase inhibition
2010/12/22
Dermal absorption of chlorpyrifos, an organophosphate insecticide is important because of its use in agriculture and control of household pests. The objectives of this study are to investigate fi rst...