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Mutations of the forkhead transcription factor FOXP2 gene have been implicated in inherited speech-and-language disorders, and specific Foxp2 expression patterns in neuronal populations and neuronal ...
A canine patient with osteosarcoma of the sacrum was subjected to low-field magnetic resonance imaging with the following sequences: FSE, SE, 3D HYCE, X BONE, Fast STIR, GE STIR and Gradient Echo. Due...
There are no randomised control trials to guide the management of patients with potentially resectable lung metastases from osteosarcoma and soft tissue sarcoma, however evidence from retrospective co...
Recently we have been performing biological reconstruction for malignant bone tumors of the extremities using frozen autografts. Here we present a case treated with free vascularized fibular graft (FV...
The canine osteosarcoma is characterized by being an aggressive bone tumor that affects mainly large dogs, middle-aged and male, accounting for 80-85% of bone tumors and 5-6% of all tumors. The risk o...
Background: Osteosarcoma is the most frequent highly malignant bone tumor with a peak incidence in the second decade of life. Although survival rate increased up to 60-70% within the last 10 years, th...
Background: Osteosarcoma is the most frequent highly malignant bone tumor with a peak incidence in the second decade of life. Although survival rate increased up to 60-70% within the last 10 years, th...
Current treatment of osteosarcoma is associated with poor prognosis, especially due to the increased risk of developing other cancers with chemotherapy. Therefore, new safe effective treatment strateg...
Background: Dendritic cells (DCs) are the strongest antigen presenting cells (APCs). They can present antigen to T lymphocytes in vivo and in vitro, and induce cytotoxic T lymphocyte (CTL) reactions. ...
The daytime and nighttime dispositions of high dose (12 g/m 2 ) methotrexate were examined in 8 osteosarcoma patients. The plasma and renal clearances, urine pH values and area under the curves were c...
Chondroblastic osteosarcoma (COS), a subgroup of intramedullary osteosarcoma, is usually located in the knee region of the body. It is most common in adolescents and early adulthood. COS has similar c...
We present a case of osteosarcoma arising from an osteochondroma of the right tibia in a 71 year old man. The radiographic studies were suggestive of a malignant lesion. Histologic examination showed ...
It is sometimes difficult to recognize a jaw lesion as osteosarcoma, ossifying fibroma or ‎fibrous dysplasia in routine hematoxylin and ‎eosin staining and a more accurate technique is nee...

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