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Pancreatic cancer, which affects about 60,000 Americans every year, is one of the deadliest forms of cancer. After diagnosis, fewer than 10 percent of patients survive for five years.
Sweet-beverage consumption and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
epidemiology juice and nectar pancreatic cancer prevention risk factors soft drinks sweet beverages sugary drinks
2018/12/14
Background: The consumption of sweet beverages has been associated with greater risk of type 2 diabetes and obesity, which may be involved in the development of pancreatic cancer. Therefore, it has be...
Integrated psychosocial and supportive care needed for patients with pancreatic cancer
Pancreatic cancer disease cancer morbidity and mortality
2017/2/22
Pancreatic cancer is acknowledged as one of the most challenging diseases in the 21st century. Despite the recent focus on research and novel therapies, by 2030 pancreatic cancer is projected to be th...
Palliative care in advanced pancreatic cancer
Patients with advanced pancreatic cancer treatment pancreatic cancer pathophysiology
2017/2/22
The management of patients with advanced pancreatic cancer often requires a multi-disciplinary approach with individualised therapy. Addressing the underlying causes of several of the troublesome symp...
The changing landscape of systemic therapy in advanced pancreatic cancer
Pancreatic cancer disease congenital resistant to treatment
2017/2/22
Pancreatic cancer is a highly lethal disease due to its late presentation and its innate resistance to treatment. Although much research has been conducted in order to discover and develop new therape...
Radiotherapy in locally advanced pancreatic cancer
Radiation therapy the treatment mode advanced pancreatic cancer radiation therapy
2017/2/22
While radiotherapy was considered an important treatment modality in locally advanced pancreatic cancer for several decades, the presentation of the LAP 07 trial results have impressed a concept that ...
The role of radiotherapy in pancreatic cancer is controversial. Its utility in treatment has been investigated in a number of clinical settings, including before and after surgery for operable cancers...
Inherited pancreatic cancer
Pancreatic cancer genetic tumor susceptibility syndrome genetic pancreatic cancer
2017/2/22
Up to 10% of pancreatic cancer cases have a heritable component. Some of these are clearly defined tumour predisposition syndromes known as hereditary pancreatic cancers, but most are familial cases, ...
Novel therapeutics and preclinical imaging for pancreatic cancer – view from the lab
Pancreatic cancer damaging disease tumor microenvironment fibrosis and cancer cells
2017/2/22
Pancreatic cancer is a devastating disease with a five-year survival rate of 6%. A key driver of disease progression is the tumour microenvironment, which is characterised by fibrosis. A dynamic inter...
Role of the microenvironment in chronic pancreatitis and pancreatic cancer
Chronic pancreatitis exocrine pancreas inflammatory bowel disease pancreatic ductal adenocarcinoma enzyme acini pancreatic stellate cell activation
2017/2/22
Chronic pancreatitis, an inflammatory disease of the exocrine pancreas, has been reported to be a major risk factor for the development of pancreatic ductal adenocarcinoma. Evidence from pre-clinical ...
Pancreatic cancer-an overview
Pancreatic adenocarcinoma diagnosis other cancers pancreatic cancer cancer
2017/2/22
Adenocarcinoma of the pancreas* takes the lives of 2500 Australians annually and because of the devastating effects of its diagnosis, has long been the poor cousin to other cancers. People with pancre...
Inhibiting protein clearance to induce cell death in tuberous sclerosis and pancreatic cancer
Ral 4-phenylbutyric acid 4-PBA
2015/5/25
Sequestration at the aggresome and degradation through autophagy are two approaches by which a cell can counteract the toxic effect of misfolded proteins. Tuberous sclerosis (TS) and cancer cells can ...
An inhibitor of the mitotic kinase, MPS1, is selective towards pancreatic cancer cells
CIN70 MPS1 kinase inhibitor pancreatic cancer
2015/5/21
The abysmal five year pancreatic cancer survival rate of less than 6% highlights the need for new treatments for this deadly malignancy. Cytotoxic drugs normally target rapidly dividing cancer cells b...
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis in Pancreatic Cancer: A Prospective Pilot Study of Safety Using 10 mL versus 20 mL Alcohol
EUS-CPN alcohol pancreatic cancer
2014/12/11
Background. The dose of alcohol used in EUS-CPN is not standardized. The objective was to compare the safety of 20 mL alcohol versus 10 mL alcohol during EUS-CPN for patients with pancreat...
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis in Pancreatic Cancer: A Prospective Pilot Study of Safety Using 10 mL versus 20 mL Alcohol
EUS-CPN alcohol pancreatic cancer
2014/12/3
Background. The dose of alcohol used in EUS-CPN is not standardized. The objective was to compare the safety of 20 mL alcohol versus 10 mL alcohol during EUS-CPN for patients with pancreat...