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Academy of Mathematics and Systems Science, CAS Colloquia & Seminars：Cross-linked Peptide Identification Using a Protein-feedback Method
蛋白质 反馈法 交联肽
2023/11/7
Improving the sensitivity of protein-protein interaction detection and protein structure probing is a principal challenge in cross-linking mass spectrometry (XL-MS) data analysis. In this talk, we pro...
PeakSelect: preprocessing tandem mass spectra for better peptide identification
preprocessing tandem mass spectra peptide identification
2010/12/17
We present a new preprocessing method, PeakSelect, to improve the accuracy and efficiency of
Tandem Mass-Spec peptide (protein) identification. The fundamental difference between noise and fragment i...
Mining Tandem Mass Spectral Data to Develop a More Accurate Mass Error Model for Peptide Identification,
Spectral Data Mass Error Model Peptide Identification
2010/12/17
The assumption on the mass error distribution of fragment ions plays a crucial role in
peptide identification by tandem mass spectra. Previous mass error models are the
simplistic uniform or normal ...
Beyond Shared Peak Count: Finding and Using Correlations in MS/MS Data for Peptide Identification
Beyond Shared Peak Count Correlations MS/MS
2010/12/14
Shared Peak Count (SPC), i.e. the number of matched peaks between the experimental MS/MS spectrum and the theoretical one predicted from a peptide sequence in the database, is a widely used scoring me...
Exploiting the kernel trick to correlate fragment ions for peptide identification via tandem mass spectrometry,
correlate fragment ions peptide identification tandem mass spectrometry
2010/12/14
The correlation among fragment ions in a tandem mass spectrum is crucial in reducing stochastic mismatches
for peptide identification by database searching. Until now, an efficient scoring algorithm ...