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南京农业大学农学院《Molecular Plant》发表万建民院士团队“The RNA binding protein EHD6 recruits the m6A reader YTH07 and sequesters OsCOL4mRNA into phase-separated ribonucleoprotein condensates to promote rice flowering”（图）
万建民 蛋白 相分离过程
2024/6/11
2024年5月9日，万建民院士团队与北京大学贾桂芳团队合作在Molecular Plant发表了题为The RNA binding protein EHD6 recruits the m6A reader YTH07 and sequesters OsCOL4mRNA into phase-separated ribonucleoprotein condensates to promote ric...
Structural insights into Arabidopsis ethylene response factor 96 with an extended N-terminal binding to GCC box
AP2/ERF ERF 96 GCC box EDLL motif Protein structure Fluorescence polarization assay
2024/1/11
The phytohormone ethylene is widely involved in many developmental processes and is a crucial regulator of defense responses against biotic and abiotic stresses in plants. Ethylene-responsive element ...
Multifunctional novel rosin derivatives based on dehydroabietylamine with metal ion sensing and DNA/BSA binding activities
Rosin derivative DNA binding BSA interaction Metal ion recognition
2023/12/6
Three novel rosin derivatives based on dehydroabietylamine which is an important modified product of rosin,?pyridine?and substituted phenol were synthesized and fully characterized. The DNA binding st...
A Picea wilsonii NAC transcription factor, PwNAC1, interacts with RNA-binding protein PwRBP1 and synergistically enhances drought and salt tolerance of transgenic Arabidopsis
Picea wilsonii Transcription factor PwNAC1 PwRBP1 Abiotic stress ABA signaling
2023/11/16
NAC transcription factors play crucial roles in plant resistance to a variety of adverse circumstances. Here, we characterized a NAC transcription factor PwNAC1 from Picea wilsonii and subcellular loc...
One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, m...
A human neutralizing antibody targets the receptor binding site of SARS-CoV-2
Preventive medicine SARS-CoV-2 Viral infection
2020/6/11
An outbreak of the coronavirus disease 2019 (COVID-19)1–3, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)4 spread globally. Countermeasures are needed to treat and prevent ...
Key Residues of the Receptor Binding Motif in the Spike Protein of SARS-CoV-2 That Interact With ACE2 and Neutralizing Antibodies
SARS-CoV-2 cross-neutralizing antibody receptor binding motif spike protein substitution mutation
2020/6/11
Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein binds the host receptor angiotens...
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Breaking the Binding: Attacks on the Merkle Approach to Prove Liabilities and its Applications
proof of liabilities Maxwell protocol summation Merkle tree
2018/11/30
Proofs of liabilities are used for applications, function like banks or Bitcoin exchanges, to prove the sums of money in their dataset that they should owe. The Maxwell protocol, a cryptographic proof...
Binding language: Structuring sentences through precisely timed oscillatory mechanisms
alpha and beta oscillations EEG language syntactic binding
2018/3/5
Syntactic binding refers to combining words into larger structures. Using EEG, we investigated the neural processes involved in syntactic binding. Participants were auditorily presented two-word sente...
Next-gen sequencing identifies non-coding variation disrupting miRNA binding sites in neurological disorders
SCZ ASD
2017/8/28
Understanding the genetic factors underlying neurodevelopmental and neuropsychiatric disorders is a major challenge given their
prevalence and potential severity for quality of life. While large-scal...
Adjusting retinol-binding protein concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
anemia inflammation meta-analysis nutritional assessment retinol-binding protein vitamin A deficiency
2018/11/15
Background: The accurate estimation of the prevalence of vitamin A deficiency (VAD) is important in planning and implementing interventions. Retinol-binding protein (RBP) is often used in population s...
Demographic, lifestyle, and genetic determinants of circulating concentrations of 25-hydroxyvitamin D and vitamin D–binding protein in African American and European American women
African American European American racial disparity vitamin D vitamin D–binding protein
2018/11/14
Background: Vitamin D may have anticancer activities. The high prevalence of vitamin D deficiency in African Americans (AAs) may be a contributing factor to the cancer health disparities between AAs a...
Study reveals the multitasking secrets of an RNA-binding protein
multitasking secrets RNA-binding protein
2017/4/27
Researchers from Princeton University and the National Institute of Environmental Health Sciences have discovered how a fruit fly protein binds and regulates two different types of RNA target sequence...
Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo)
Fatty Acid-binding Protein4 (FABP4) Single-Nucleotide Polymorphism (SNP)
2017/3/8
This study identifies single-nucleotide polymorphisms (SNP) or gene combinations that affect the flavor and quality of Korean cattle (Hanwoo) by using the SNP Harvester method.