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Using GWAS Data to Identify Copy Number Variants Contributing to Common Complex Diseases
Using GWAS Data Identify Copy Number Variants Contributing Common Complex Diseases
2010/11/16
Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these poly...
CFA as a method for genetic association studies in complex diseases
Configural Frequency Analysis (CFA) genetic association studies complex diseases allele frequencies haplotype configurations
2010/1/4
Genetic factors contribute to the development of a variety of complex diseases, which are presumably determined by interactions of multiple polymorphic gene loci. Therefore, the genetic research has t...
Statistical advances and challenges for analyzing correlated high dimensional SNP data in genomic study for complex diseases
Complex disease High dimensional data Single Nucleotide Polymorphism Statistical methods
2009/2/11
Recent advances of information technology in biomedical sciences and other applied areas have created numerous large diverse data sets with a high dimensional feature space, which provide us a tremend...