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Haplotype based association study between t-PA gene and essential hypertension
Haplotype based association study t-PA gene essential hypertension
2009/4/20
Several previous studies have shown that essential hypertension (EH) is associated with fibrinolysis. Tissue plasminogen activator (t-PA) plays a key role in fibrinolysis. Thus, it is possible that ...
马铃薯密码子用法分析及其在t-PA基因密码子改造上的应用Analysis of Codon Usage in Potato and Its Application in the Modification of t-PA Gene
马铃薯 t-PA 密码子用法 优越密码子 密码子改造
2008/1/10
摘要 采用bioperl-1.0 工具在红旗LINUX系统下自编了密码子分析软件;通过对马铃薯98个蛋白质编码基因序列(codon DNA sequence)的分析,计算出了马铃薯的密码子用法,并确定出了马铃薯的4个高表达优越密码子;依据马铃薯密码子用法和高表达优越密码子分析结果,对t-PA基因序列进行了密码子的改造,得到了具有马铃薯密码子使用特点的t-PA基因序列,从而为以马铃薯为生物反应器高效...