搜索结果: 1-15 共查到“知识库 实验病理学”相关记录22条 . 查询时间(3.657 秒)
Comparison of serum levels of IL-6, IL-8, TNF-?, C reactive protein and heat shock protein 70 in patients with active and inactive Behçet's disease
chemokine C-reactive protein cytokine heat shock protein interleukin Behç et's disease
2010/2/24
The results of our study suggest that serum IL-6, IL-8, TNF-, and CRP levels are increased in patients with active Behçets disease. HSP 70 levels in both active and inactive disease groups were...
Reiter's Syndrome in a Patient with Polyarthritis and Nail Involvement
Reiter's syndrome Nail involvement
2009/12/14
An 8-year old boy with polyarthritis and nail involvement is presented in this report. Nail involvement in Reiter's syndrome is a rare condition that may include painless erythematous nduration of the...
CLINICO-PATHOLOGY AND ULTRASTRUCTURAL ETUDY OF NEPHROPATHY CHANGES DUE TO LUPUS ERYTHEMATOSIS DISSEMINATUS
CLINICO-PATHOLOGY ULTRASTRUCTURAL ETUDY NEPHROPATHY CHANGES LUPUS ERYTHEMATOSIS DISSEMINATUS
2009/12/2
Nephrotic syndrome _ Nephrotic syndrome is found in 30% of all of the cases of systematic LE. Nephropathy Changes Due to Lupus Erythematosus 21 (15,16) in peripheral blood may confirm definitively lup...
ErbB信号与蛋白激酶B在快速起搏所致猴心衰心肌细胞损伤中的作用
心力衰竭 细胞凋亡
2009/11/30
为了研究ErbB受体与蛋白激酶B在心力衰竭发生机制中的作用，建立快速起搏诱导恒河猴心力衰竭模型。采用颈总动脉插管技术，测定左心室最大压力上升速度(LVdp/dtmax)、左心室舒张末期压(LVEDP)、左心室收缩末期压(LVSP)等血流动力学指标；采用电化学发光免疫测定法观察脑钠肽(BNP)含量；采用RT-PCR方法测定ErbB2、蛋白激酶B(PKB)、Bcl-xl mRNA表达水平；采用West...
N-甲酰溶肉瘤素对小鼠精原细胞的损害作用
N-甲酰溶肉瘤素 小鼠精原细胞 损害作用
2009/11/30
用计算细胞数的方法,观察了N-甲酰溶肉瘤素对小鼠造精细胞的损害作用。结果表明,在造精细胞系列中,精原细胞对N-甲酰溶肉瘤素最为敏感,表现为细胞变性、核分裂消失、细胞数极度减少,在各型精原细胞中,又以B型更为敏感。考虑到N-甲酰溶肉瘤素是一种在临床对精原细胞瘤有显著疗效的药物,本文讨论了药物对精原细胞的损害作用和对精原细胞瘤的治疗作用的相关性.
Evaluation of Angiogenesis in Colorectal Carcinoma by CD34 Immunohistochemistry Method and its Correlation with Clinicopathologic Parameters
Angiogenesis antigens CD34 colorectal neoplasm immunohistochemistry clinical pathology
2009/11/26
The basic pathogenic step in the process of tumor growth, invasion and metastasis is tumor-induced angiogenesis. The aim of this study was to evaluate the angiogenesis in colorectal carcinoma by micro...
是动脉粥样硬化的主要致病因素，但是OxLDL必须通过其特异性受体，凝集素样氧化型低密度脂蛋白受体-１（LOX-1）的介导才能发挥作用。近来研究发现，众多因素能调控LOX-1的病理表达，内皮细胞吞噬与LOX-1结合OxLDL后触发一系列信息通路，调控转录因子的表达，使粘附分子、炎症因子等表达上调，活性氧表达降低，导致内皮损伤、动脉粥样硬化等疾病形成，LOX-1是众多事件的初始阶段，所以可能成为重要的...
目的：采用肺成纤维细胞三维立体培养技术，直接观察弹力蛋白酶和基质金属蛋白酶对肺的主要成分之一胶原组织的降解作用。方法： 用明胶酶谱法和Western blotting法测定MMP-1、2、 3、9和TIMP-1和2 (金属蛋白酶抑制因子), 同时测定胶原含量。结果： TNF-α和IL-1β诱导培养在立体胶原内的肺成纤维细胞产生MMP-1、3和9, 但是只引起少量胶原降解（2.8%±1.5%, P...
目的：探讨整合素αvβ3、组织因子(tissue factor, TF)及血管内皮细胞生长因子（vascular endothelial growth factor, VEGF）在激光诱导的大鼠脉络膜新生血管（choroidal neovascularization, CNV）组织中的表达。方法：随机选取成年雄性棕色挪威大鼠25只，一眼为实验组，经氩激光（波长532 nm）光凝诱导CNV形成，另一...
基因芯片筛选肝硬化相关基因
基因芯片 肝硬化 相关基因
2009/7/29
目的: 应用基因芯片技术研究肝硬化相关基因的基因表达谱.方法: 乙肝肝硬化组织为实验组，以正常肝组织为对照. 按一步法抽提实验组和对照组标本的总RNA并纯化mRNA; 将等量的实验组和对照组标本mRNA分别逆转录合成荧光分子掺入的cDNA做探针,混合后杂交1 568点BioDoorChipLiver-16S芯片.经严格洗片后用ScanArray3000扫描仪扫描芯片获取荧光信号图像,计算机分析后比...
The Effect of Erythropoietin in Acute Pancreatitis:An Experimental Study
Department of Surgery,Ankara Numune Teaching and Research Hospital,Ankara-TURKEY Department of Pathology,Ankara Numune Teaching and Research Hospital,Ankara-TURKEY
2009/6/19
Background: Although the pathogenesis of acute pancreatitis is not clearly known, the most frequently mentioned factors are proinflammatory cytokines and nitric oxide (NO), which is stimulated by bact...
Reproducibility of Fuhrman Nuclear Grading of Renal Cell Carcinoma: A Preliminary Study
Fuhrman nuclear grade,renal cell carcinoma,reproducibility
2009/5/20
Background: The aim of this study was to evaluate intraobserver and interobserver reproducibility of Fuhrman nuclear grading of renal cell carcinoma. Methods: Pathology slides from 46 cases of renal c...
TAFI基因编码区C291T的多态性与脑梗死的相关性研究
凝血酶激活的纤溶抑制物基因 单核苷酸多态性 脑梗死
2011/7/13
TAFI基因编码区C291T的多态性与脑梗死的相关性研究。
有关内乳淋巴结照射的ＥＯＲＴＣⅢ期临床实验质控经验介绍
内乳淋巴结照射 ＥＯＲＴＣⅢ期临床实验 质控经验
2009/2/12
ＥｌｅｎａＭｕｓａｔ在最近的欧洲癌症杂志（Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｃａｎｃｅｒ）上发表一篇题目为“Ｑｕａｌｉｔｙ ａｓｓｕｒａｎｃｅ ｉｎ ｂｒｅａｓｔ ｃａｎｃｅｒ：ＥＯＲＴＣ ｅｘｐｅｒｉｅｎｃｅｓ ｉｎ ｔｈｅ ｐｈａｓｅ Ⅲ ｔｒｉａｌ ｏｎ ｉｒｒａｄｉａｔｉｏｎ ｏｆ ｔｈｅ ｉｎｔｅｒｎａｌ ｍａｍｍａｒｙ ｎｏｄｅｓ”的文章。本文就其主要内容作一简单介绍。