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A context dependent pair hidden Markov model for statistical alignment
Comparative genomics Contextual alignment DNA sequence alignment EM algorithm Insertion deletion model
2011/9/6
Abstract: This article proposes a novel approach to statistical alignment of nucleotide sequences by introducing a context dependent structure on the substitution process in the underlying evolutionar...
A non-parametric hidden Markov model for climate state identification
Hidden Markov models non-parametric two-state model
2009/3/12
Hidden Markov models (HMMs) can allow for the varying wet and dry cycles in the climate without the need to simulate supplementary climate variables. The fitting of a parametric HMM relies upon assump...