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Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study
betaine pregnancy birth weight infants adiposity
2018/12/18
Background: Betaine supplementation results in lower body weight and fat mass and higher lean mass in animals and adult humans. However, the relation between maternal betaine status and offspring birt...
Microbial protein targets: towards understanding and intervention
Microbial protein structure Biochemical analyses
2016/7/29
The symposium will bring together leading expertise in protein structure determination, biochemical characterisation and chemical biology to explore the most recent advances in the understanding
of p...
The foundation for supramolecular chemistry is in nature; by studying these archetypes, chemists have devised methods of recreating these complex interactions in the laboratory. Of particular interest...
Towards the isolation of esterase and amidase catalytic antibodies: Examination of germinal center diversity by cloning and sequence analysis of genes encoding monoclonal antibodies elicited by a transition state analogue
Esterase catalytic antibodies amidase amide ester hydrolysis reaction hybrid cells B cells the TSA induced antibodies genes cells cell lines
2014/12/11
In this study, a transition state analogue (TSA) approach was employed for the isolation of catalytic antibodies with esterase or amidase activity. The TSA used in this study, phosphonamidate, mimics ...
An Integrative Approach Towards Understanding The Structure- Function Relationship Of The Epigenetic Regulator Methyl Cpg Binding Protein 2
Pure sciences Biological sciences Epigenetic regulator Methyl CpG Binding protein 2 Binding dynamics of caps Chromatin architectural proteins (caps) Intrinsically disordered protein Nucleosome Protein folding
2014/12/10
Methyl CpG binding protein 2 (MeCP2) is a methylated DNA binding protein which, when mutated, leads to a severe neurodevelopmental disorder known as Rett syndrome (RTT). In the present work I have sho...
The University of Queensland’s largest alumni endowment gift to contribute towards advanced research into reproductive medicine（图）
reproductive medicine IVF
2014/7/11
A $10.5 million gift from an internationally renowned clinician and research leader will advance The University of Queensland’s global contributions to reproductive medicine.
Towards a learning-theoretic analysis of spike-timing dependent plasticity
dependent plasticity learning-theoretic analysis spike-timing
2012/11/26
This paper suggests a learning-theoretic perspective on how synaptic plasticity benefits global brain functioning. We introduce a model, the selectron, that (i) arises as the fast time constant limit ...
Towards a theoretical understanding of false positives in DNA motif finding
theoretical understanding false positives DNA motif finding
2011/1/5
Detection of false-positive motifs is one of the main causes of low performance in motif finding methods. It is generally assumed that false-positives are mostly due to algorithmic weakness of motif-f...
The differences between natural and artificial life. Towards a definition of life
natural artificial life
2011/1/6
It is high time to openly and without finalism define the dangerous but needed term 'purposeful information', whose quantity is an Eigen information value. Using the term 'biological information' in i...
In vivo Antimutagenicity of Dadih Probiotic Bacteria towards Trp-P1
Potential Probiotic E. faecium Dadih Antimutagenicity
2016/4/28
In vitro acid- and bile-tolerant lactic acid bacteria isolated and identified from Indonesian traditional fermented milk dadih might be considered as potential probiotic strains after further characte...