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Identification and characterization of altered mitochondrial protein acetylation in Friedreich's ataxia cardiomyopathy
Identification and characterization mitochondrial protein acetylation
2015/5/21
Friedreich’s Ataxia (FRDA) is a rare and poorly understood autosomal recessive disease caused by a pathological deficiency of the mitochondrial protein frataxin. Patients suffer neurodegeneration, ata...
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
Mapping Dynamic Histone Acetylation Patterns Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
2010/11/15
Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency ...
Global Histone H4 Acetylation of IGF1 and GH Genes in Lungs of Somatic Cell Cloned Calves
Histone H4 Acetylation Somatic Cloned Calves IGF1 GH Lung
2016/4/21
Histone acetylation modification is one key mechanism in the regulation of gene activation. In this study, we investigated the global levels of histone H4 acetylation of insulin like growth factor I (...