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Multiple barriers in forced rupture of protein complexes
Multiple barriers forced rupture of protein complexes Biological Physics
2012/5/3
Curvatures in the most probable rupture force ($f^*$) versus log-loading rate ($\log{r_f}$) observed in dynamic force spectroscopy (DFS) on biomolecular complexes are interpreted using a one-dimension...
Multiple barriers in forced rupture of protein complexes
Multiple barriers forced rupture of protein complexes Biological Physics
2012/4/20
Curvatures in the most probable rupture force ($f^*$) versus log-loading rate ($\log{r_f}$) observed in dynamic force spectroscopy (DFS) on biomolecular complexes are interpreted using a one-dimension...
Stochastic emergence of multiple intermediates detected by single-molecule quasi-static mechanical unfolding of protein
single-molecule detection protein folding molecular force microscopy molecular dynamics energy landscape
2010/12/2
Experimental probing of a protein-folding energy landscape can be challenging, and energy landscapes comprising multiple intermediates have not yet been defined. Here, we quasi-statically unfolded sin...