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ONTOLOGY-DRIVEN AND NETWORK–ENABLED SYSTEMS BIOLOGY CASE STUDIES
bioinformatics Integration of genomics
2015/5/27
With the progress in high-throughput technologies and bioinformatics in recent years, it is possible to determine to what extent genetic or environmental manipulation of a biological system affects th...
Tensegrity and Motor-Driven Effective Interactions in a Model Cytoskeleton
Tensegrity Motor-Driven Effective Interactions Model Cytoskeleton Biological Physics
2012/4/24
Actomyosin networks are major structural components of the cell. They provide mechanical integrity and allow dynamic remodeling of eukaryotic cells, self-organizing into the diverse patterns essential...
Translocation of a polymer chain driven by a dichotomous noise
Translocation polymer chain driven dichotomous noise
2012/2/28
We consider the translocation of a one-dimensional polymer through a pore channel helped by a motor driven by a dichotomous noise with time exponential correlation. We are interested in the study of t...
An acoustically-driven biochip - Impact of flow on the cell-association of targeted drug carriers
acoustically-driven biochip - Impact flow cell-association targeted drug carriers
2011/8/11
Abstract: The interaction of targeted drug carriers with epithelial and endothelial barriers in vivo is largely determined by the dynamics of the body fluids. To simulate these conditions in binding a...
Heat Dissipation and Nonequilibrium Thermodynamics of Quasi-Steady States and Open Driven Steady State
Heat Dissipation Nonequilibrium Thermodynamics Quasi-Steady States Open Driven Steady State
2011/9/13
We develop a comparative thermodynamic theory, based on master-equation description of driven chemical reactions, for quasi-steady-state (QSS) and open-system nonequilibrium steady-state (NESS) sustai...
Comparative study of the ion flux pathway in stator units of proton- and sodium-driven flagellar motors
membrane protein ion flux bacteria locomotion motility molecular motor taxis
2010/12/2
Flagellar motor proteins, MotA/B and PomA/B, are essential for the motility of Escherichia coli and Vibrio alginolyticus, respectively. Those complexes work as a H+ and a Na+ channel, respectively and...