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One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, m...
Researchers from Princeton University and the National Institute of Environmental Health Sciences have discovered how a fruit fly protein binds and regulates two different types of RNA target sequence...
Abstract Timothy E. Breen Ph.D. A DATABASE FOR NUCLEAR RECEPTOR DNA BINDING SITES A database has been developed for nuclear receptor DNA binding sites and the corresponding nuclear receptor DNA ...
Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to ...
The MDM2-p53 feedback loop is a well-characterized pathway. p53 is a transcription factor and regulates the transcriptional expression of genes that encode proteins responsible for cellular senescen...
Glycogen, a branched polymer of glucose, acts as an intracellular carbon and energy reserve in many tissues and cell types. The breakdown of glycogen by hormonally regulated degradation involving the ...
Intrinsically disordered proteins are proteins characterized by lack of stable tertiary structures under physiological conditions. Evidence shows that disordered proteins are not only highly involved ...
The proteasome is responsible for breaking down the majority of the proteins in the cell. However, a complete understanding of how this large multi-subunit protease is assembled is currently lacking. ...
专著信息 书名 Letter to the Editor:1H, 13C and 15N resonance assignments and secondary strucutre of ADR6 DNA-binding Domain 语种 英文 撰写或编译 作者 Xiaoming Tu,Jihui Wu,Yingqi Xu and Yunyu Shi 第一作者单位 出版社 J. of Biomo...
专著信息 书名 Coling, expression, secondary structure charaterization of HMG box 1 of hUBF from E. coli and its binding to DNA 语种 英文 撰写或编译 作者 Wulin Yang,Wangyoong Zeng,Danzhou,Yunyu Shi 第一作者单位 出版社 Biochimic...
期刊信息 篇名 Evaluating the binding affinities of NF-κB p50 homodimer to the wild-type and single-nucleotide mutant Ig-κB sites by the unimolecular dsDNA microarray. 语种 英文 撰写或编译 作者 Jin K. Wang,Tong X. Li,Y...
期刊信息 篇名 (3) Synthesis, biological evaluation and DNA binding properties of novel bleomycin analogues. 语种 英文 撰写或编译 作者 徐志栋,杨铭 第一作者单位 刊物名称 Bioorganic and Medicinal Chemistry Letters 页面 2003, 13(15): 2595...
Background: Treatment of hyperlipidemic patients with fish oil results in an increase in plasma LDL cholesterol despite a marked decrease in the LDL precursor, VLDL. Objective: We studied the relat...

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