搜索结果: 1-15 共查到“生物工程 Human”相关记录27条 . 查询时间(0.109 秒)
Engineers devise a way to selectively turn on RNA therapies in human cells（图）
人类细胞 RNA疗法 治疗性蛋白质 癌症治疗
2023/6/21
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences...
The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT's Whitehea...
New technique helps engineer water filters, human tissues（图）
New technique engineer water filters human tissues
2019/10/22
Scientists at Rutgers University have developed a technique to turn proteins into never-ending patterns that look like flowers, trees or snowflakes. The study, which appears in the journal Nature Chem...
Researchers wirelessly manipulate gene, step toward reprogramming the human genome（图）
manipulate gene toward reprogramming human genome
2019/10/23
A new University at Buffalo-led study supported by NSF describes how researchers wirelessly controlled FGFR1 -- a gene that plays a key role in how animals grow from embryos to adults -- in lab-grown ...
第八届DNA损伤应答与人类疾病国际研讨会（isDDRHD-2017）（8th international symposium on DNA Damage Response&Human Disease）
第八届 DNA损伤应答与人类疾病 国际研讨会
2017/8/31
第八届DNA损伤应答与人类疾病国际研讨会（international symposium on DNA Damage Response & Human Disease, isDDRHD-2017）将于2017年10月27-29日在深圳大学召开。DNA损伤应答与人类疾病国际研讨会（isDDRHD）是由许兴智教授和Zhao-Qi Wang院士于2010年共同发起，旨在为DNA修复领域的中国学者与国际主...
Slow motion waves of jumping genes in the human genome
Slow motion waves jumping genes human genome
2016/11/29
Nature is full of parasites—organisms that flourish and proliferate at the expense of another species. Surprisingly, these same competing roles of parasite and host can be found in the microscopic mol...
Development and Application of a Mass Spectrometry-Based Quantitative Assay for Apolipoprotein M in Human and Mouse Serum
Mass Spectrometry Cholesterol Apolipoprotein M MS-Based Assay
2015/5/26
Apolipoprotein M (apoM) is necessary for the formation of lipid-poor preβ-HDL particles, the initial precursor of HDL and acceptors of cholesterol efflux from peripheral cells. An assay to quantify ap...
HUMAN CARBOXYLESTERASE 2 SPLICE VARIANTS: EXPRESSION, ACTIVITY, AND ROLE IN THE METABOLISM OF IRINOTECAN AND CAPECITABINE
Carboxylesterase alternative splicing colorectal cancer
2015/5/25
Carboxylesterases (CES) are enzymes that metabolize a wide variety of compounds including esters, thioesters, carbamates, and amides. In humans there are three known carboxylesterase genes CES1, CES2,...
ELUCIDATING THE ROLE OF REDOX EFFECTS AND THE KU80 C-TERMINAL REGION IN THE REGULATION OF THE HUMAN DNA REPAIR PROTEIN KU
DNA-PKcs regulation Ku NHEJ
2015/5/25
DNA double strand breaks (DSB) are among the most lethal forms of DNA damage and can occur as a result of ionizing radiation (IR), radiomimetic agents, endogenous DNA-damaging agents, etc. If left unr...
TRANSCRIPTIONAL REGULATION OF THE HUMAN ALCOHOL DEHYDROGENASES AND ALCOHOLISM
exon arrays differential gene expression alternative splicing
2015/5/25
Alcohol dehydrogenase (ADH) genes encode proteins that metabolize ethanol to acetaldehyde. Humans have seven ADH genes in a cluster. The hypothesis of this study was that by controlling the levels of ...
In Vivo Analysis of Human LHX3 Gene Regulation
Gene Regulation Pituitary Combined Pituitary Hormone Deficiency LHX3
2015/5/25
LHX3 is a transcription factor important in pituitary and nervous system development. Patients with mutations in coding regions of the gene have combined pituitary hormone deficiency (CPHD) that cause...
The LHX3 transcription factor is essential for pituitary gland and nervous system development in mammals. In humans, mutations in the LHX3 gene underlie combined pituitary hormone deficiency (CPHD) di...
Human Niemann-Pick Type C2 Disease Protein Expression, Purification and Crystallization
Niemann-Pick type C2 NPC2 Structure Expression Crystallization Purification
2014/12/12
Niemann-Pick type C2 (NPC2) protein is a soluble protein that binds unesterified cholesterol. The protein helps transport unesterified cholesterol in tandem with the membrane protein Niemann-Pick type...
Interconversion of the Specificities of Human Lysosomal Enzymes
Fabry Schindler α-GAL α-Galactosidase α-NAGAL α-N-acetygalactosaminidase
2014/12/12
Fabry disease (FD) is an X-linked recessive lysosomal storage disorder (LSD) known to affect approximately 1 in every 40,000 males, and a smaller number of females. FD results from a deficiency of fun...
人胰岛素基因在体内外表达的研究The Expression of Human Insulin Gene in vitro and in vivo
人胰岛素基因 基因治疗 肝细胞 糖尿病
2008/1/29
摘要利用定点突变人胰岛素基因，以脂质体载体和质粒不同比例形成的复合物进行体内外转染。体外转染鼠肝细胞，G418进行筛选，利用放免法测定培养液中胰岛素含量；体内通过肝门脉注射，测定模型鼠血糖及转染后7天时血液中胰岛素的含量，结果显示目的基因已转入肝细胞，且体内外转染都有一定量的成熟胰岛素表达，体外转染中质粒与脂质体比为1∶6转染后24h表达量最高为10.45μIU/ml，体内转染使模型鼠的糖尿病症状...