搜索结果: 1-15 共查到“基因工程 Human”相关记录15条 . 查询时间(0.109 秒)
The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT's Whitehea...
Researchers wirelessly manipulate gene, step toward reprogramming the human genome（图）
manipulate gene toward reprogramming human genome
2019/10/23
A new University at Buffalo-led study supported by NSF describes how researchers wirelessly controlled FGFR1 -- a gene that plays a key role in how animals grow from embryos to adults -- in lab-grown ...
第八届DNA损伤应答与人类疾病国际研讨会（isDDRHD-2017）（8th international symposium on DNA Damage Response&Human Disease）
第八届 DNA损伤应答与人类疾病 国际研讨会
2017/8/31
第八届DNA损伤应答与人类疾病国际研讨会（international symposium on DNA Damage Response & Human Disease, isDDRHD-2017）将于2017年10月27-29日在深圳大学召开。DNA损伤应答与人类疾病国际研讨会（isDDRHD）是由许兴智教授和Zhao-Qi Wang院士于2010年共同发起，旨在为DNA修复领域的中国学者与国际主...
Slow motion waves of jumping genes in the human genome
Slow motion waves jumping genes human genome
2016/11/29
Nature is full of parasites—organisms that flourish and proliferate at the expense of another species. Surprisingly, these same competing roles of parasite and host can be found in the microscopic mol...
HUMAN CARBOXYLESTERASE 2 SPLICE VARIANTS: EXPRESSION, ACTIVITY, AND ROLE IN THE METABOLISM OF IRINOTECAN AND CAPECITABINE
Carboxylesterase alternative splicing colorectal cancer
2015/5/25
Carboxylesterases (CES) are enzymes that metabolize a wide variety of compounds including esters, thioesters, carbamates, and amides. In humans there are three known carboxylesterase genes CES1, CES2,...
TRANSCRIPTIONAL REGULATION OF THE HUMAN ALCOHOL DEHYDROGENASES AND ALCOHOLISM
exon arrays differential gene expression alternative splicing
2015/5/25
Alcohol dehydrogenase (ADH) genes encode proteins that metabolize ethanol to acetaldehyde. Humans have seven ADH genes in a cluster. The hypothesis of this study was that by controlling the levels of ...
In Vivo Analysis of Human LHX3 Gene Regulation
Gene Regulation Pituitary Combined Pituitary Hormone Deficiency LHX3
2015/5/25
LHX3 is a transcription factor important in pituitary and nervous system development. Patients with mutations in coding regions of the gene have combined pituitary hormone deficiency (CPHD) that cause...
The LHX3 transcription factor is essential for pituitary gland and nervous system development in mammals. In humans, mutations in the LHX3 gene underlie combined pituitary hormone deficiency (CPHD) di...
人胰岛素基因在体内外表达的研究The Expression of Human Insulin Gene in vitro and in vivo
人胰岛素基因 基因治疗 肝细胞 糖尿病
2008/1/29
摘要利用定点突变人胰岛素基因，以脂质体载体和质粒不同比例形成的复合物进行体内外转染。体外转染鼠肝细胞，G418进行筛选，利用放免法测定培养液中胰岛素含量；体内通过肝门脉注射，测定模型鼠血糖及转染后7天时血液中胰岛素的含量，结果显示目的基因已转入肝细胞，且体内外转染都有一定量的成熟胰岛素表达，体外转染中质粒与脂质体比为1∶6转染后24h表达量最高为10.45μIU/ml，体内转染使模型鼠的糖尿病症状...
应用实时定量RT-PCR技术检测b地中海贫血珠蛋白基因的表达Quantitative Analysis of Human Globin Gene Expression in b-thalassemia Using Real-Time RT-PCR
地中海贫血/遗传学 珠蛋白基因 基因表达 实时定量RT-PCR
2008/1/6
摘要
为了定量检测 b 地中海贫血(b 地贫)的 a、b 和γ珠蛋白基因表达水平， 提取正常成人对照组、正常胎儿对照组和b 地贫患者组组成的样本 DNA，采用反向点杂交法（RDB）分析b 地贫各种突变类型；提取样本RNA用于进行针对a、b 和γ珠蛋白基因的荧光实时定量RT-PCR（FQ RT-PCR）。根据FQ RT-PCR原理，设计合成分别对应于a、b 和γ珠蛋白基因的3对引物和3条荧光探针，...
人线粒体tRNALeu(UUR)基因A3243G点突变对其亮氨酰化活性的影响Effects of A3243G Point Mutation on Aminoacylation of Human Mitochondrial tRNALeu(UUR)
人线粒体tRNALeu(UUR) A3243G点突变 氨酰化 体外转录 人线粒体亮氨酰tRNA结合酶
2007/12/30
摘要化学法合成人线粒体野生型与A3243G点突变型tRNALeu(UUR)基因,体外转录生成相应的tRNALeu(UUR),表达并纯化人线粒体亮氨酰tRNA合成酶(mtLeuRS),用mtLeuRS催化野生型与突变型tRNALeu(UUR)与亮氨酸结合，分别检测两种类型tRNALeu(UUR)的氨酰化动力学常数。结果表明，野生型tRNALeu(UUR)的Km/Kcat仅为突变型tRNALeu(UU...
纪念DNA双螺旋结构模型发表50周年、祝贺人类基因组计划最终完成一部无法绕过的经典文献The Human Genome《人类基因组——我们的DNA》。
专著信息
书名
Construction and significance of directional expression cDNA library from human NB4 cell.
语种
英文
撰写或编译
作者
CHEN Gang (陈 刚),ZHANG Wanggang (张王刚),FU Jie (付 杰),CAO Xingmei (曹星梅),ZHAO Wanhong (赵万红)H...
期刊信息
篇名
“Beijing Region” (3pter-D3S3397) of the Human Genome: Complete sequence and analysis
语种
英文
撰写或编译
撰写
作者
王晶、张猛、吴清发、黄薇、董伟、胡松年、杨焕明、于军、汪建等
第一作者单位
中科院北京基因组研究所
刊物名称
Science in China (Series C)
页面
200...
KU researchers explore human disease through tiny roundworm（图）
human disease roundworm muscular dystrophy
2006/12/8
Dec. 1, 2006，LAWRENCE — University of Kansas researchers are learning a lot about humans from a tiny roundworm.Researchers commonly use the worm, Caenorhabditis elegans, or C. elegans, to study a rang...