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Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet around 70% don’t respond to these medications, which work by removing the “brakes” on the immune system’s response to a...
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by ...
Researchers at MIT and Dana-Farber Cancer Institute have developed a new way to determine whether individual patients will respond to a specific cancer drug or not. This kind of test could help doctor...
As tumors grow within an organ, they also release cells that enter the bloodstream. These cells can travel to other organs, seeding new tumors called metastases.
Extracellular vesicles (EVs), nanometer-sized messengers that travel between cells to deliver cues and cargo, are promising tools for the next generation of therapies for everything from autoimmune an...
重庆医科大学附属第一医院欧云生教授带领的科研团队撰写对论文“An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors”【Science 2020 367(6476):446-453】进行评论的论文在线刊登于Science期刊网站的官方平台。第一作者为重庆医科大学2014级临床医学...
T cells are the immune soldiers at the frontline of the battle with infiltrating pathogens that seek to cause disease. A new studypublished in Nature Biomedical Engineering describes a ...
2019年11月13日,浙江大学医学院附属口腔医院王慧明教授团队在STEM CELLs(干细胞领域权威期刊之一)上在线发表题为“KLF2+ stemness maintains human mesenchymal stem cells in bone regeneration”的研究论文,首次提出采用KLF2作为人骨髓间充质干细胞(hMSCs)体外标志物,并研究KLF2+hMSCs在血管再生和骨组...
We thank Prof. Peng Zhou (Wuhan, China) for kindly providing materials and thank Yan Wu and Weijuan Shang for experimental assistance. This work was supported by the Strategic Priority Research Progra...
Anti-aging proteins have long been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study by researchers at the Gladstone Institutes now ...
Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy. However, good pharmacolo...
Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the Univers...
A team of researchers has engineered smart protein molecules that can reprogram white blood cells to ignore a self-defense signaling mechanism that cancer cells use to survive and spread in the body. ...
A study by scientists at the University of Arizona and the University of Pittsburgh may hold the key to targeting dormant — or inactive —cancer cells, which are resistant to chemotherapy and other tre...
A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the blood stream and then killing these cells, according...

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