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探讨热休克转录因子1(HSF1)调控微小RNA-195a-3p (miR-195a-3p)对心肌微血管内皮细胞血管新生功能的影响,旨在阐明HSF1基因缺失加重压力超负荷下心脏重构的病理分子机制。方法:压力超负荷动物模型采用小鼠主动脉弓缩窄(TAC),辅以心脏超声功能评价。在体实验分组为HSF1基因敲除(HSF1-/-)小鼠假手术组、C57BL/6野生型(WT)小鼠假手术组、HSF1-/-小鼠TAC...
HSF1-mediated oxidative stress response to menadione in Saccharomyces cerevisiae KNU5377Y3 by using proteomic approach
Saccharomyces cerevisiae KNU5377Y3 HSF1 Gene Expression Menadione Redox
2013/1/28
The hat shock transcription factor HSF1 inthe yeast Saccharomyces cerevisiae regulates a wide range of genes and functions in diverse cellular reactions. To investigate the physiological response of H...
HSF1-mediated oxidative stress response to menadione in Saccharomyces cerevisiae KNU5377Y3 by using proteomic approach
Saccharomyces cerevisiae KNU5377Y3 HSF1 Gene Expression Menadione Redox
2013/1/28
The hat shock transcription factor HSF1 inthe yeast Saccharomyces cerevisiae regulates a wide range of genes and functions in diverse cellular reactions. To investigate the physiological response of H...