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Pancreatic neuroendocrine tumours are rare tumours that can either present with syndromes from excess hormonal production or from mass effect – from the primary or metastases. They vary widely in clin...
Hypoxia is a condition in which an area of the body or a tissue is deprived of sufficient supply of oxygen. The lack of nutrients in a hypoxic tissue generally causes apoptosis but some cells are able...
Giant cell tumours (GCTs) of bone have been described as the most challenging benign bone tumors. It is very unusual for GCT to occur in patients younger than 20 yrs or older than 55 years. GCT is see...
Neuroendocrine tumours have posed a challenge for the development of research and management strategies because of their rarity and heterogeneity, both from clinical and molecular perspectives. Classi...
Metastatic cancers are often resistant to conventional chemotherapy and radiotherapy, reflecting an unmet need for novel therapeutic approaches to inhibit metastasis. Growing evidence highlights the i...
Circulating tumour cells – often referred to as a ‘liquid biopsy’ for cancer – can be found in a large proportion of patients with breast cancer that has spread to other organs. Changes in circulating...
Recent advances in genomic technology, in particular gene expression profiling, may elucidate novel tumour markers or signatures that will predict how various tumours will behave and respond to vario...
This paper reviews the evaluation of malignancy and prognostic parameters used in gastrointestinal stromal tumours (GIST). Incorporated is a case report of a duodenal GIST treated at our institutio...
Microarray-based transcript profiling is a technique used to measure the steady-state levels of gene expression on a genome-wide scale in a cell or tissue. The technology essentially involves making a...
With the rapid establishment of immunohistology as an indispensable adjunct to histological diagnosis, an ever-increasing range of antibodies has been developed to complement highly sensitive methods ...
The dendritic cell (DC), an uncommon type of bone marrowderived leukocyte, is widely acknowledged as the most effective antigen presenting cell (APC) and has the unique capacity to initiate and cont...
By tracking changes in patients’ blood, Cambridge scientists have created a new way of looking at how tumours evolve in real-time and develop drug resistance. The research was published in the print e...
We present a case of a Myxoid Meningioma noticed in a 43-year-old woman. The patient, who had no noteworthy medical antecedents, showed repeated focal epileptic crisis. Imaging studies (MR and CT) sho...
Malignant peripheral nerve sheath tumour of the maxilla - Report of a case and review of literature.
A new study by scientists at The University of Nottingham's Children's Brain Tumour Research Centre, funded by the Samantha Dickson Brain Tumour Trust, shows that prolonged and slow diagnosis can mak...

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