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Fas(APO21/ CD95) 是神经生长因子受体(NGFR) / 肿瘤坏死因子受体( TNFR) 超家族成员之一,在多种细胞中表达。由于Fas 信号途径在细胞凋亡中起重要作用,因此近年来此途径日益成为人们的研究热点。当Fas 与其配体( FasL) 或竞争性抗体(Fas mAb) 结合后,可通过细胞毒效应、Fas 死亡结构域相关蛋白(FADD) 和半胱氨酸蛋白酶(caspases) 及其他机制...
Expression of Fas Antigen (CD95) on Human Leukemic Cells and Assessment of Apoptosis on Fas+ and Fas-Samples by Flowcytometry Method
Human Leukemic Cells Human Leukemic Cells
2010/4/26
Regulation of normal cell growth and turnover is balanced between cell pro¬liferation, cell differentiation and apoptosis.
A disruption of this balance is thought to be an important event leading...