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Genetic Impact of a Butyrophilin-like 2 (BTNL2) Gene Variation on Specific IgE Responsiveness to Dermatophagoides farinae (Der f) in Japanese
BTNL2 Dermatophagoides farinae (Der f) specific IgE
2010/11/16
Controlling for gender, age, smoking, and the presence of asthma, multiple logistic regression analyses showed that homozygosity of the rs2076530 A allele, which has been reported to be a risk allele ...
Airway responsiveness to acetylcholine or capsaicin in immature and mature guinea pigs in vivo
aging airway obstruction asthma capsaicin neuropeptide
2010/11/25
Non-specific airway hyperresponsiveness is a characteristic feature of bronchial asthma. Airway reactivity to cholinergics may change with age during childhood. The present paper describes tests to se...
Effect of repeated antigen inhalation on airway inflammation and bronchial responsiveness to acetylcholine in interleukin-5 transgenic mice
bronchial hyperresponsiveness eosinophils interleukin-5 mice
2010/11/25
Bronchial hyperresponsiveness (BHR) is a characteristic feature of bronchial asthma, yet its precise mechanism remains obscure. Human studies have demonstrated that T helper 2 cytokines, including int...
Mouse bone marrow-derived mast cells acquire responsiveness to substance P after co-culture with 3T3 fibroblasts in the presence of stem cell factor
co-culture mast cells stem cell factor substance P 3T3 fibroblasts
2010/11/29
Connective tissue-type mast cells degranulate in response to a neurogenic peptide, substance P, whereas bone marrow-derived mast cells (BMMC) do not respond to this stimulant when prepared with a comb...
Bronchial and nasal responsiveness in atopic asthma and allergic rhinitis patients: Relationship of local responsiveness to cytokine production by peripheral blood mononuclear cells
allergic rhinitis atopy bronchial asthma bronchial responsiveness interleukin-4 interleukin-5 nasal responsiveness
2010/11/29
To investigate the relationship between local responsiveness and allergic symptoms, bronchial and nasal responsiveness were measured in the following four groups of subjects: (i) bronchial asthma pati...