搜索结果: 1-9 共查到“医学细胞生物学 Development”相关记录9条 . 查询时间(0.187 秒)
清华大学医学院郑撼球课题组在《基因与发育》(Genes & Development)发表合作论文揭示抑制乳腺癌转移的关键因子(图)
清华大学医学院 郑撼球 基因与发育 Genes & Development 论文 揭示抑制乳腺癌 转移 关键因子
2020/10/22
SNAI2蛋白是SNAIL转录因子家族重要的成员之一。最初在胚胎发育的研究中,发现其对关键发育阶段中细胞的形态改变和细胞迁移发挥重要的作用。随后的研究中发现上皮来源的肿瘤细胞只有在上调以SNAI2为代表的转录因子之后,将自己改变为类似成纤维细胞的“窄长”状,并去除细胞之间的粘连,才能获得强大的组织浸润和迁移能力,从而帮助肿瘤细胞实现离开原位组织并最终发生癌症转移。而在病人预后最差的三阴性乳腺癌中,...
Study:Changing the environment within bone marrow alters blood cell development
Changing the environment bone marrow blood cell development
2017/3/14
Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.The findings, reported in th...
LymphTF Database- A Database of Transcription Factor Activity in Lymphocyte Development
LymphTF Database DNA bioinformatics
2015/5/26
Study of the transcriptional regulation of lymphocyte development has advanced greatly in the past 15 years. Owing to improved techniques and intense interest in the topic, a great many interactions b...
CIS REGULATORY MODULE DISCOVERY IN TH1 CELL DEVELOPMENT
TH1 cell development STAT4 ChIP-on-chip ChIP-Seq
2015/5/26
Immune response enables the body to resist foreign invasions. The Inflammatory response is an important aspect in the immune response which is articulated by elements such as cytokines, APC, T-cell an...
TRANSGENIC USE OF SMAD7 TO SUPPRESS TGFβ SIGNALING DURING MOUSE DEVELOPMENT
heart development doxycycline inducible
2015/5/25
Neural crest cells (NCC) are a multipotent population of cells that form at the dorsal region of neural tube, migrate and contribute to a vast array of embryonic structures, including the majority of ...
DIFFERENTIAL ROLE OF PI-3KINASE p85 (α & β) REGULATORY SUBUNITS IN MAST CELL DEVELOPMENT
Cell cycle -- Regulation Enzymes
2015/5/25
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
Reconstitution of mouse inner ear sensory development from pluripotent stem cells
Inner ear Pluripotent stem cells Hair cells
2015/5/21
The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound. Hearing loss and imbalance are primarily caused by degeneration of the mechanosensitive hair cells i...
Dynamics of Cellular Behavior During Development and Disease
James Nelson Stanford University School of Medicine USA
2014/7/25
We are pleased to announce Cold Spring Harbor Asia conference on Dynamics of Cellular Behavior During Development and Disease which will be held in Suzhou, China, located approximately 60 miles west o...
Suplatast Tosilate Inhibits Human Mast Cell Development from Cord Blood Progenitors
cord blood progenitors human mast cells stem cell factor suplatast tosilate
2010/11/19
Background: Localized mast cell accumulation has been reported in a number of human diseases. Suplatast tosilate has been reported to inhibit IL-3-dependent murine mast cell development, and therefore...