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Discovery of novel regulators of aldehyde dehydrogenase isoenzymes
ALDH2 Characterization High-throughput docking approach
2015/5/25
Recent work has shown that specific ALDH isoenzymes can contribute to the underlying pathology of different diseases. Many ALDH isozymes are important in oxidizing reactive aldehydes resulting from li...
Novel regulation of neuronal genes implicated in Alzheimer disease by microRNA
Alzheimer APP BACE1 microRNA post-transcriptional gene regulation amyloid fetal neurons
2015/5/21
Alzheimer disease (AD) results, in part, from the excess accumulation of the amyloid-β peptide (Aβ) as neuritic plaques in the brain. The short Aβ peptide is derived from a large transmembrane precurs...
Detection and Prevalence of Polyoma Virus BK among Iranian Kidney Transplant Patients by a Novel Nested-PCR
BK virus Renal transplant recipients Prevalence Iran
2015/9/21
Background: BK virus is an increasingly recognized pathogen in transplant recipient patients associated with nephropathy and emerged as a cause of allograft failure linked to immunosuppressive regimen...
Diabetes foot ulcers: A novel treatment strategy
Diabetic Foot Ulcer Treatment Activation Th-1 cells
2010/5/7
Foot ulcers are common in 12-25 percent of diabetic patients. Preventing, controlling and treating of these kind chronic wounds are of the major clinical challenges. Evidence based documents revealed ...