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Protective effect of homovanillyl alcohol on cardiovascular disease and total mortality: virgin olive oil, wine, and catechol-methylathion
cardiovascular homovanillyl alcohol hydroxytyrosol traditional Mediterranean diet virgin olive oil
2018/11/14
Background: Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Hydroxytyrosol-related foods have been shown to protect against cardiovascular disease (CVD).
Substituting whole grains for refined grains in a 6-wk randomized trial has a modest effect on gut microbiota and immune and inflammatory markers of healthy adults
gut microbiota healthy adults immune inflammation whole grains
2018/11/13
Background: Observational studies suggest an inverse association between whole-grain (WG) consumption and inflammation. However, evidence from interventional studies is limited, and few studies have i...
Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention
Chinese folic acid hyperglycemia hypertension stroke
2018/11/13
Background: Diabetes is a known risk factor for stroke, but data on its prospective association with first stroke are limited. Folic acid supplementation has been shown to protect against first stroke...
No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial
sugar-sweetened beverages systemic inflammation adipose tissue inflammation fructose intestinal permeability
2018/12/3
Background: Sugar-sweetened beverage (SSB) consumption and low-grade chronic inflammation are both independently associated with type 2 diabetes and cardiovascular disease. Fructose, a major component...
Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions
acylcarnitines cardiovascular disease Mediterranean diet metabolomics PREDIMED
2018/11/30
Background: Previous studies have suggested that metabolite profiles of elevated acylcarnitines were associated with increased risk of cardiovascular disease (CVD) in populations with established coro...
Astaxanthin has no effect on arterial stiffness, oxidative stress, or inflammation in renal transplant recipients: a randomized controlled trial (the XANTHIN trial)
carotid artery intima-media thickness F2-isoprostanes pentraxin-3 pulse wave velocity vascular function
2018/11/26
Background: There is evidence that renal transplant recipients have accelerated atherosclerosis that is manifest by increased cardiovascular morbidity and mortality. The high incidence of atherosclero...
Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on gastrointestinal metabolism of ingested glucose
glucose surgery tracers weight loss intestine metabolism diabetes
2018/11/23
Background: Data from studies conducted in animal models suggest that intestinal glucose uptake and metabolism are upregulated after Roux-en-Y gastric bypass (RYGB) surgery, which contributes to a wei...
Effect of Fresh Royal Jelly Ingestion on Glycemic Response in Patients With Type 2 Diabetes
Royal Jelly Hyperglycemia Glycemic Control
2015/11/9
Background: Type 2 diabetes is the fourth major public health problem worldwide. Royal Jelly (RJ) insulin-like activity and blood glucose modulating properties have been reported in animal and healthy...
Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma
arachidonic acid Calotropis gigantea ovalbumin
2015/7/21
The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxyge...
Effect of Advanced Access Scheduling on Processes and Intermediate Outcomes of Diabetes Care and Utilization
diabetes open access process of care outcomes utilization
2014/12/11
BACKGROUND The impact of open access (OA) scheduling on chronic disease care and outcomes has not been studied. OBJECTIVE To assess the effect of OA implementation at 1 year on: (1) diabetes care proc...
Sex Differences in Diabetes Risk and the Effect of Intensive Lifestyle Modification in the Diabetes Prevention Program
diabetes risk gender diabetes prevention programs lifestyle modification
2014/12/11
OBJECTIVE—In participants of the Diabetes Prevention Program (DPP) randomized to intensive lifestyle modification (ILS), meeting ILS goals strongly correlated with prevention of diabetes in the group ...
Investigating Antithyroid Effects of Propylthiouracil on the Ischemia and Reperfusion Injury in Rat’ Kidney and Determining the Role of Nitric Oxide in Mediating this Effect
Ischemia Reperfusion Rat,Renal Transplantation
2015/10/15
Background: Renal ischemia/reperfusion injury (IRI) is a major problem in renal transplantation, which occurs during the process of organ retrieval and storage, and is closely associated with acute re...
Additional Effect of Diabetes Mellitus Type 2 on the Risk of Coronary Artery Disease: Role of Serum Adiponectin
Coronary Artery Disease Diabetes Mellitus Type 2 Interleukin-6
2015/10/10
Background: Adiponectin, an adipocyte-derived hormone, is implicated in diabetes mellitus type 2 and atherosclerosis. The study was designed to investigate whether serum adiponectin levels in patients...
Effect of Early Treatment With Tirofiban on Initial TIMI Grade 3 Flow of Patients With ST Elevation Myocardial Infarction
Myocardial Infarction Tirofiban Percutaneous Coronary Intervention Angiography
2015/10/10
Background:: Before primary percutaneous coronary intervention (PCI) in patients with ST elevation myocardial infarction (STEMI), it is not clear whether a routine early administration of glycoprotein...
Bone Loss with Multiple Sclerosis:Effect of Glucocorticoid Use and Functional Status
Multiple sclerosis Bone mineral density Ambulation Steroid
2015/9/22
Background: Emerging data suggest a significantly increased prevalence of low bone mineral density (BMD) in men and women with multiple sclerosis (MS) compared to age matched controls. This study was ...