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Depletion of Thymus-Derived CD4+CD25+ T Cells Abrogates the Suppressive Effects of α-galactosylceramide Treatment on Experimental Allergic Conjunctivitis
allergic conjunctivitis eosinophils regulatory T cells thymus α-galactosylceramide
2010/11/17
α-GalCer treatment significantly suppressed EC in the thymus-intact mice that had not been treated with anti-CD25 Ab. In contrast, α-GalCer treatment of thymectomized and anti-CD25 Ab-treated mice did...
Effects of Probiotics on the Immune System and Allergic Diseases
adaptive immunity allergic diseases commensals epithelial cells innate immunity intestinal microbiota probiotics
2010/11/22
Intestinal microbiota play a crucial role in the development of mucosal tolerance and adaptation. Perturbations in microbiota composition are strongly associated with allergies and asthma in westerniz...