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Animal model of isolated gonadotropin deficiency. II. Morphologic responses to LHRH immunoneutralization
hypogonadotropic-hypogonadism LHRH dog immunohypophysectomy testis prostate excurrent
2009/2/19
Morphologic changes in the male reproductive system of mongrel dogs immunized against LHRH were quantitated using linear measurements and morphometric techniques at the light-microscopic level. Two ...
Animal model of isolated gonadotropin deficiency. I. Hormonal responses to LHRH immunoneutralization
hypogonadotropic-hypogonadism luteinizing hormone releasing hormone pituitary serum LH
2009/2/19
Five intact male mongrel dogs, characterized by an episodic secretory pattern of LH and normal serum testosterone concentrations, were actively immunized against LHRH by subcutaneous injections of 2...
There are numerous tools available to modify the genetic makeup of animals. They are being used to good advantage for studying basic biological phenomena. Within the decade, biomedical products deri...
Intratesticular testosterone concentration following intratunical administration in the hypogonadal animal
Testosterone tunica vaginalis hypogonadism infertility
2009/2/13
The serum and intratesticular testosterone concentration (ITC) after testosterone administration in the tunica vaginalis (TV) sac compared to parenteral administration was studied in 20 dogs that were...
Effects of Medical or Surgical Castration on Erectile Function in an Animal Model
Androgens trabecular smooth muscle corpus cavernosum veno-occlusion vardenafil leuprolide acetate
2008/12/19
The goal of this study was to investigate the effects of medical castration (luteinizing hormone-receptor hormone [LH-RH] agonist treatment) or surgical castration on erectile function in an animal ...
Efficacy of Vardenafil and Sildenafil in Facilitating Penile Erection in an Animal Model
Pelvic nerve-mediated erection intracavernosal pressure
2008/12/3
Vardenafil and sildenafil are potent and specific phosphodiesterase type 5 (PDE 5) inhibitors. In human penile cavernosal smooth muscle cells, we have previously shown that vardenafil has a lower bi...