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Expression of c-KIT and its ligand, stem cell factor, in normal and subfertile human testicular tissue
Germ cells proto-oncogenes testis stem cells
2009/2/16
The c-KIT proto-oncogene encodes for a transmembrane receptor and is associated with maturation of several cell types, including germ cells. The ligand of the receptor has been identified as stem ...
Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes
Spermatocyte spermatid acrosome maturation arrest
2008/12/29
It has already been demonstrated that the Notch signaling system is essential for gametogenesis in the adult germ line of Caenorhabditis elegans. However, the role of the Notch signaling system in m...
Identification and regulation of receptor tyrosine kinases Rse and Mer and their ligand Gas6 in testicular somatic cells
Identification regulation receptor tyrosine kinases Mer Gas6 testicular somatic cells
2008/12/25
Receptor tyrosine kinases act to convey extracellular signals to intracellular signaling pathways and ultimately control cell proliferation and differentiation. Rse, Axl, and Mer belong to a newly i...
Receptor Isoform and Ligand-Specific Modulation of Dihydrotestosterone-Induced Prostate Specific Antigen Gene Expression and Prostate Tumor Cell Growth by Estrogens
Androgen receptor androgens estrogen receptor
2008/12/23
Androgens via the androgen receptor (AR) play crucial roles in prostate physiology and pathophysiology. These androgen actions can be either inhibited or potentiated by estrogens. The mechanisms of ...
Genetic Analysis of Kit Ligand Functions During Mouse Spermatogenesis
Genetic Analysis Kit Ligand Functions Mouse Spermatogenesis
2008/12/22
Kit ligand (KITL), also known as mast cell growth factor (MGF), stem cell factor (SCF), and Steel factor,1 and its receptor, KIT, are essential for embryonic and postnatal development of both male and...
Progesterone Receptor Availability in Mouse Spermatozoa During Epididymal Transit and Capacitation：Ligand Blot Detection of Progesterone-Binding Protein
Acrosome reaction sperm maturation
2008/12/19
The goals of the present study were to determine the availability of progesterone (P4) receptor (P4r) in mouse sperm during maturation and capacitation and to make the first steps toward a character...
Progesterone Receptor Availability in Mouse Spermatozoa During Epididymal Transit and Capacitation：Ligand Blot Detection of Progesterone-Binding Protein
Acrosome reaction sperm maturation
2008/12/19
The goals of the present study were to determine the availability of progesterone (P4) receptor (P4r) in mouse sperm during maturation and capacitation and to make the first steps toward a character...