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Anti-viral medication to prevent HCC development: where are we now?
Hepatitis B virus malignancy
2015/3/30
Hepatitis B virus was the first human virus unequivocally associated with malignancy. Long-term persistent infection with hepatitis B virus can result in the development of chronic liver disease, cirr...
Risk of hepatocellular carcinoma in chronic viral hepatitis
hepatocellular carcinoma chronic viral hepatitis
2015/3/30
Chronic viral hepatitis B and C infections are the diseases associated with the highest risk for developing hepatocellular carcinoma. These infections are prevalent worldwide. Many factors modulate th...
Trends in chronic viral hepatitis: notifications, treatment uptake and advanced disease burden
treatment uptake advanced disease
2015/3/30
Since the introduction of mandatory notification in the early 1990s, around 110,000 and 260,000 cases of hepatitis B and hepatitis C respectively, have been reported through public health surveillance...
VIRAL MODULATION OF MHC CLASS II-MEDIATED ANTIGEN PRESENTATION
MHC class II Vaccinia virus
2015/5/21
Vaccinia virus (VV) has been used as a vaccine, yet safety concerns remain due to its viral immunoevasive properties. Among these, VV infection of antigen presentation cells (APC) perturbs MHC class I...