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Pancreatic cancer is a devastating disease with a five-year survival rate of 6%. A key driver of disease progression is the tumour microenvironment, which is characterised by fibrosis. A dynamic inter...
Targeting uncontrolled cell proliferation and resistance to DNA damaging chemotherapeutics using small molecule inhibitors of proteins involved in these pathways has significant potential in cancer tr...
The DNA Base Excision Repair (BER) pathway repairs DNA damaged by endogenous and exogenous agents including chemotherapeutic agents. Removal of the damaged base by a DNA glycosylase creates an apurini...
Surgery remains the standard of care for most rectal cancer as it offers the best chance of cure. However, for patients with early stage low rectal cancers there are several treatment options availabl...
The mechanism by which vertebroplasty is effective in providing pain relief is unclear, but may involve destruction of nerve endings consequent upon the injection of bone cement into the vertebral bod...
Scientists from the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago Medical Center are shaking up the world of materials science and cancer research on the cover ...
A team of researchers led by the Whitehead and Broad Institutes has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed n...
The identification of tumor antigens recognized by cytotoxic T-lymphocytes and subsequent clinical trials using peptide immunization have shown tumor regression in advanced malignant melanoma patients...
Aim: The aim of this study was to compare the antioxidative status in patients with colorectal cancer and healthy controls, based on measurements made using a novel method. Materials and Methods: The ...
期刊信息 篇名 (1) Novel Bleomycin Analogues Synthesis, Antitumor Activity, and Interaction with DNA. 语种 英文 撰写或编译 作者 徐志栋,杨铭 第一作者单位 刊物名称 Helvetica Chimica Acta 页面 2004, 87(11): 2834-2 出版日期 2004年 月 日 文章标识(ISSN...

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