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Critically ill patients are characterized by a hypermetabolic state, a catabolic response, higher nutritional needs, and a decreased capacity for utilization of parenteral substrate.
Carbohydrate and fat may differ in their ability to support energy-requiring physiologic processes, such as protein synthesis and growth. If so, varying the constituents of infant formula might be ...
Vagal stimulation in response to nutrients is reported to elicit an array of digestive and endocrine responses, including an alteration in postprandial lipid metabolism.
The onset of cystic fibrosis–related diabetes mellitus (CFDM) is often associated with a decline in clinical and nutritional status.
Metabolic adjustments occur during pregnancy and lactation to support fetal growth and milk synthesis; however, the effect of body composition and hormonal milieu on these changes is poorly underst...
Background: After major burns, patients exhibit an intense catabolism, and the wounds require surgery and grafting for closure. Complications, such as weight loss and delayed wound healing, are worsen...
Twelve healthy, dietarily unrestrained women participated in a single-blind, placebo-controlled, randomized trial with crossover design. For 3 d before and throughout a 36-h stay in a respiration cham...
Intake of an alcohol-rich meal stimulates energy expenditure but suppresses fat oxidation and leptin more than do isoenergetically dense meals rich in protein, carbohydrate, or fat. Despite difference...
One milligram of nicotine has a pronounced thermogenic effect, which can be increased by ≈100% by adding 100 mg caffeine. Increasing the nicotine dose to 2 mg does not increase the thermogenic effect ...
Background: Several epidemiologic studies suggest that snacking may play an etiologic role in obesity.Objective: We assessed the behavioral and metabolic consequences of a high-carbohydrate ...
Background: The carnitine O-palmitoyltransferase I (EC 2.3.1.21) inhibitor etomoxir inhibits fatty acid oxidation, and hepatic fatty acid oxidation has been suggested to be a metabolic ...
Background: High-fat and high-carbohydrate diets lead to insulin resistance, gastrointestinal adaptation, and high plasma triacylglycerol concentrations. It is unclear, however, how rapidly these...
Background: Different dietary fats are metabolized differently in humans and may influence energy expenditure, substrate oxidation, appetite regulation, and body weight regulation.Objective: ...
Background: ()-Hydroxycitrate (HCA), a competitive inhibitor of ATP-citrate lyase, should reduce the extramitochondrial acetyl-CoA pool. It has been hypothesized that HCA ingestion can reduce malon...

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