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Feature reduction for improved recognition of subcellular location patterns in fluorescence microscope images
proteomics subcellular location pattern subcellular location features
2009/12/23
The central goal of proteomics is to clarify the mechanism by which each protein in a given cell type carries out itsfunction. Automated protein subcellular location determination by fluorescence micr...
Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated Analysis of Fluorescence Microscope Images
Automated Analysis Fluorescence Microscope Images
2009/12/22
Determination of the functions of all expressed proteins
represents one of the major upcoming challenges in
computational molecular biology. Since subcellular
location plays a crucial role in prote...
Automated Recognition of Patterns Characteristic of Subcellular Structures in Fluorescence Microscopy Images
Patterns Characteristic Subcellular Structures Fluorescence
2009/12/22
Methods for numerical description and subsequent
classification of cellular protein localization
patterns are described. Images representing the
localization patterns of 4 proteins and DNA were
ob...
High-Speed Fluorescence Imaging and Intensity Profiling of Femtosecond-Induced Calcium Transients
Imaging Calcium Transients
2009/9/8
We have demonstrated a combined imaging system, where the physiology of biological specimens can be imaged and profiled at 10–20 frames per second whilst undergoing femtosecond laser irradiation. Indi...
Automated Analysis of Fluorescence Microscopy Images to Identify Protein-Protein Interactions
Fluorescence Microscopy Images Interactions
2009/9/8
The identification of protein interactions is important for elucidating biological networks. One obstacle in comprehensive interaction studies is the analyses of large datasets, particularly those con...
A Fast Reconstruction Algorithm for Fluorescence Optical Diffusion Tomography Based on Preiteration
Fluorescence Optical Diffusion Tomography Preiteration
2009/9/7
Fluorescence optical diffusion tomography in the near-infrared (NIR) bandwidth is considered to be one of the most promising ways for noninvasive molecular-based imaging. Many reconstructive approache...
Fluorescence Modified Chitosan-Coated Magnetic Nanoparticles for High-Efficient Cellular Imaging
Magnetic nanoparticle Fluorescence Chitosan Magnetic resonance imaging
2010/7/16
Labeling of cells with nanoparticles for living detection is of interest to various biomedical applications. In this study, novel fluorescent/magnetic nanoparticles
were prepared and used in high-eff...
Magnetic nanocomposites of Fe3O4/SiO2-FITC with pH-dependent fluorescence emission
Nanocomposites Core–shell structure Magnetic nanoparticles Fluorescence
2010/7/16
This paper describes the formation of magnetic and fluorescent nanocomposite particles which consist of superparamagnetic Fe3O4 core, SiO2 shell and organic dye (FITC) coating layer on their surface. ...