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Differentiation-associated alteration in sensitivity to apoptosis induced by (-)-epigallocatechin-3-O-gallate in HL-60 cells
Differentiation-associated alteration sensitivity
2009/12/16
Green tea and its constituent (-)-epigallocatechin-3-O-gallate (EGCG) are known to have apoptosis-inducing activity on tumor cells including human leukemia HL-60 cells, providing an explanation for th...
Analysis of Differences in Sensitivity of Animals to an IKr Specific Blocker Using Simulation
potassium IKr blocker E-4031 KCNE1 Luo-Rudy model
2009/6/9
In this study, we analyzed the relation of APD prolongation induced by an IKr specific blocker and the KCNE1 expression level with simulations using cardiac membrane action potential models that diff...